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Xylb xylulokinase [ Rattus norvegicus (Norway rat) ]

Gene ID: 316067, updated on 11-Apr-2024

Summary

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Official Symbol
Xylbprovided by RGD
Official Full Name
xylulokinaseprovided by RGD
Primary source
RGD:1307372
See related
Ensembl:ENSRNOG00000014168 AllianceGenome:RGD:1307372
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable xylulokinase activity. Predicted to be involved in phosphorylation and xylulose metabolic process. Predicted to be active in cytosol. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 427.5), Liver (RPKM 248.5) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
8q32
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (127971194..128012511)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (119093466..119128858)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (128041875..128076951)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene oxidative stress responsive kinase 1 Neighboring gene uncharacterized LOC120094290 Neighboring gene MYD88, innate immune signal transduction adaptor Neighboring gene acetyl-CoA acyltransferase 1A Neighboring gene activin A receptor type 2B Neighboring gene 40S ribosomal protein S27-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism. Bunker RD, et al. J Biol Chem, 2013 Jan 18. PMID 23179721, Free PMC Article
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC124790

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables D-xylulokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables D-xylulokinase activity IEA
Inferred from Electronic Annotation
more info
  
enables D-xylulokinase activity ISO
Inferred from Sequence Orthology
more info
  
enables D-xylulokinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in D-xylose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xylulose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xylulose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in xylulose metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in xylulose metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
xylulose kinase
Names
xylulokinase homolog (H. influenzae)
NP_001028876.2
XP_006244158.1
XP_017451187.2
XP_017451188.2
XP_038937568.1
XP_038937572.1
XP_063121726.1
XP_063121727.1
XP_063121728.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033704.2 → NP_001028876.2  xylulose kinase

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q3MIF4
    UniProtKB/TrEMBL
    A0A8I5Y795
    Related
    ENSRNOP00000077183.1, ENSRNOT00000104648.1
    Conserved Domains (1) summary
    cd07776
    Location:9 → 479
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    127971194..128012511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081644.2 → XP_038937572.1  xylulose kinase isoform X7

    Conserved Domains (1) summary
    cl17037
    Location:136 → 343
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. XM_063265656.1 → XP_063121726.1  xylulose kinase isoform X2

  3. XM_017595699.3 → XP_017451188.2  xylulose kinase isoform X4

    Conserved Domains (1) summary
    cd07776
    Location:136 → 583
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

  4. XM_017595698.3 → XP_017451187.2  xylulose kinase isoform X3

    UniProtKB/TrEMBL
    G3V7T5
    Conserved Domains (1) summary
    cd07776
    Location:136 → 606
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

  5. XM_039081640.2 → XP_038937568.1  xylulose kinase isoform X1

    UniProtKB/Swiss-Prot
    Q3MIF4
    Conserved Domains (1) summary
    cd07776
    Location:136 → 606
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

  6. XM_063265658.1 → XP_063121728.1  xylulose kinase isoform X5

    UniProtKB/TrEMBL
    A6I3W3

  7. XM_063265657.1 → XP_063121727.1  xylulose kinase isoform X5

    UniProtKB/TrEMBL
    A6I3W3

  8. XM_006244096.4 → XP_006244158.1  xylulose kinase isoform X6

    UniProtKB/Swiss-Prot
    Q3MIF4
    Conserved Domains (2) summary
    PLN02669
    Location:1 → 452
    PLN02669; xylulokinase
    cd07776
    Location:1 → 401
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

RNA

  1. XR_356707.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3MIF4.1 GenPept UniProtKB/Swiss-Prot:Q3MIF4

Gene LinkOut

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