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    HLH4C Helix loop helix protein 4C [ Drosophila melanogaster ]

    Gene ID: 31397, updated on 8-Jan-2012
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    Summary

    Official Symbol
    HLH4Cprovided by Flybase
    Official Full Name
    Helix loop helix protein 4Cprovided by Flybase
    Primary source
    FLYBASE:FBgn0011277
    Locus tag
    Dmel_CG3052
    Gene type
    protein coding
    RNA name
    helix loop helix protein 4C
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bHLH36; CG3052; Dmel\CG3052; DroNHLH; EG:84H4.2
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    Genomic context

    Location :
    4C10-4C11
    Sequence :
    Chromosome: X; NC_004354.3 (4539160..4541447, complement)
    See HLH4C in Epigenomics, MapViewer

    Chromosome X - NC_004354.3Genomic Context describing neighboring genes Neighboring gene CG3081 gene product from transcript CG3081-RA Neighboring gene CG3062 gene product from transcript CG3062-RA Neighboring gene mitochondrial ribosomal protein L30 Neighboring gene CG3024 gene product from transcript CG3024-RA Neighboring gene cap binding protein 80 Neighboring gene CG15473 gene product from transcript CG15473-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation. Stevens JD, et al. Differentiation, 2008 Nov. PMID 18557763.
    2. The Drosophila basic helix-loop-helix protein DIMMED directly activates PHM, a gene encoding a neuropeptide-amidating enzyme. Park D, et al. Mol Cell Biol, 2008 Jan. PMID 17967878.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860.

    See all (14) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:57914 BioGRID:64445 Argk    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:66066 CG10053    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64023 CG11345    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:72500 CG11985    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58852 CG12708    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58579 CG12721    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58678 CG12725    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65592 CG12975    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59015 CG13001    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65192 CG13022    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62077 CG13186    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64968 CG13458    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:60007 CG13996    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65363 CG14079    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67258 CG14302    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68067 CG14543    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:72655 CG14634    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65853 CG14667    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:66582 CG14739    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61691 CG14752    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63885 CG14965    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62860 CG15109    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61128 CG15167    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59846 CG15440    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68434 CG15526    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:72662 CG15578    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63070 CG15666    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62243 CG17050    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:625088 CG17162    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67176 CG17801    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58137 CG1958    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58525 CG2371    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68397 CG31036    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:77449 CG32086    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64754 CG32100    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:72543 CG32428    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:76716 CG32581    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:57935 CG32772    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59834 CG3338    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:607119 CG34109    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63393 CG3735    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68039 CG42235    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59556 CG4896    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65115 CG4998    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61044 CG5050    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61084 CG5783    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64646 CG6163    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67517 CG6353    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67634 CG6972    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:60220 CG7231    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64700 CG7264    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61438 CG7856    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:66213 CG8145    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61412 CG8245    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:60254 CG8292    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62499 CG8414    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64872 CG8745    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59980 CG8965    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58880 CG8974    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63706 CG9173    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61309 CG9331    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58966 CG9784    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63300 CG9875    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58538 CkIIbeta    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68148 Cpr97Eb    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61540 Eaf    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62399 Ercc1    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58239 Es2    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59119 Frq2    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68060 HLHm7    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:66274 HP1e    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61671 Lcp2    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61171 Lim3    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65188 Lmpt    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:77555 LpR1    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65085 MED10    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59275 Mer    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67060 Scp2    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58206 Smox    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59325 Syx16    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63374 TBPH    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:58214 Traf6    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:64396 Zasp66    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:60337 alien    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63159 ari-2    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:57878 dgt4    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63646 emc    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62028 en    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:62282 fl(2)d    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:68952 flw    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67689 fzo    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61158 hk    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59324 l(1)G0004    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:67588 lqfR    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:66497 mRpL40    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63697 mtacp1    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65288 mus304    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:65884 noi    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61361 nompB    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:59392 slgA    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:61369 step    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:69344 sub    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63809 yellow-g    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:63430 yki    BioGRID  PubMed Two-hybrid 
    BioGRID:57914 BioGRID:77850 zormin    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the HLH4C gene: The HLH4C gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, mosquito, and C.elegans.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    sequence-specific DNA binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    regulation of transcription, DNA-dependent ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG3052 gene product from transcript CG3052-RA
    Names
    CG3052-PA
    HLH4C-PA
    helix loop helix protein 4C
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.3

      Range
      4539160..4541447, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057641.3 → NP_476989.2  helix loop helix protein 4C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4I4
      Related
      FBpp0070659, FBtr0070691
      Conserved Domains (1) summary
      cd00083
      Location:108 – 165
      Blast Score: 99
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA BT022167.1 AAY51561.1
    genomic AE014298.4 AAF45967.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q9W4I4.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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