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    Unc-76 [ Drosophila melanogaster ]

    Gene ID: 31179, updated on 9-May-2012
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    Summary

    Official Symbol
    Unc-76provided by Flybase
    Primary source
    FLYBASE:FBgn0040395
    Locus tag
    Dmel_CG3981
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH10260; CG18851; CG3981; Dmel\CG3981; Dunc-76; EG:67A9.1; l(1)G0066; l(1)G0158; l(1)G0310; l(1)G0333; l(1)G0360; unc-76; UNC-76
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    Genomic context

    Location :
    2C10-2D1
    Sequence :
    Chromosome: X; NC_004354.3 (1974645..1987129)
    See Unc-76 in Epigenomics, MapViewer

    Chromosome X - NC_004354.3Genomic Context describing neighboring genes Neighboring gene CG4061 gene product from transcript CG4061-RA Neighboring gene CG4045 gene product from transcript CG4045-RA Neighboring gene CG4025 gene product from transcript CG4025-RA Neighboring gene CG16903 gene product from transcript CG16903-RA Neighboring gene ncRNA Neighboring gene corkscrew Neighboring gene polyhomeotic distal

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Toda H, et al. Genes Dev, 2008 Dec 1. PMID 19056884.
    2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    4. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044.
    5. Evidence for a selective sweep in the wapl region of Drosophila melanogaster. Beisswanger S, et al. Genetics, 2006 Jan. PMID 16204208.

    See all (15) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. UNC-76 is required for kinesin-dependent axonal transport
      Title: The kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:57723 BioGRID:63867 CG11486    BioGRID  PubMed Two-hybrid 
    BioGRID:57723 BioGRID:65444 Grasp65    BioGRID  PubMed Two-hybrid 
    BioGRID:57723 BioGRID:59459 Pi3K21B    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the Unc-76 gene: The Unc-76 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, and C.elegans.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    kinesin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    axon cargo transport IMP
    Inferred from Mutant Phenotype
    more info
    		  
    neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		  
    phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG3981 gene product from transcript CG3981-RB
    Names
    CG3981-PA
    CG3981-PB
    Unc-76
    Unc-76-PA
    Unc-76-PB
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.3

      Range
      1974645..1987129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130625.2 → NP_569981.1  Unc-76, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W525
      Related
      FBpp0070360, FBtr0070376
      Conserved Domains (1) summary
      pfam07763
      Location:143 – 422
      Blast Score: 830
      FEZ; FEZ-like protein

    2. NM_166927.1 → NP_726792.1  Unc-76, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W525
      Related
      FBpp0070361, FBtr0070377
      Conserved Domains (1) summary
      pfam07763
      Location:143 – 422
      Blast Score: 830
      FEZ; FEZ-like protein
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014298.4 AAF45723.3
    genomic AE014298.4 AAG22388.2
    mRNA AY069376.1 AAL39521.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W525.1 GenPept
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    Additional Links

    Gene LinkOut

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