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    HLA-DPB1 major histocompatibility complex, class II, DP beta 1 [ Homo sapiens ]

    Gene ID: 3115, updated on 19-May-2012
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    Summary

    Official Symbol
    HLA-DPB1provided by HGNC
    Official Full Name
    major histocompatibility complex, class II, DP beta 1provided by HGNC
    Primary source
    HGNC:4940
    Locus tag
    DADB-22N23.4
    See related
    Ensembl:ENSG00000223865; HPRD:00832; MIM:142858; Vega:OTTHUMG00000031076
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DPB1; HLA-DP; HLA-DPB; HLA-DP1B; FLJ57621; FLJ61008
    Summary
    HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    6p21.3
    Sequence :
    Chromosome: 6; NC_000006.11 (33043703..33057473)
    See HLA-DPB1 in Epigenomics, MapViewer

    Chromosome 6 - NC_000006.11Genomic Context describing neighboring genes Neighboring gene bromodomain containing 2 Neighboring gene major histocompatibility complex, class II, DO alpha Neighboring gene major histocompatibility complex, class II, DP alpha 1 Neighboring gene ribosomal protein L32 pseudogene 1 Neighboring gene major histocompatibility complex, class II, DP alpha 2 (pseudogene) Neighboring gene collagen, type XI, alpha 2 pseudogene

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Raychaudhuri S, et al. Nat Genet, 2012 Jan 29. PMID 22286218.
    2. Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. Li J, et al. PLoS One, 2011. PMID 21904616.
    3. A directed protein interaction network for investigating intracellular signal transduction. Vinayagam A, et al. Sci Signal, 2011 Sep 6. PMID 21900206.
    4. Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. Noguchi E, et al. PLoS Genet, 2011 Jul. PMID 21814517.
    5. Identification of an HLA-DPB1*0501 restricted Melan-A/MART-1 epitope recognized by CD4+ T lymphocytes: prevalence for immunotherapy in Asian populations. Meng Z, et al. J Immunother, 2011 Sep. PMID 21760531.

    See all (268) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. The results illustrate the value of pathway-based analysis to mine genome-wide data, and point to the importance of the HLA-DPB1 locus for susceptibility to cervical cancer.
      Title: Pathway-based analysis of genetic susceptibility to cervical cancer in situ: HLA-DPB1 affects risk in Swedish women.
    2. Results confirmed that two SNPs (rs2395309 and rs9277535) in the HLA-DP loci were strongly associated with HBV infection in southern and northern Han Chinese populations, but not with HBV progression.
      Title: Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
    3. Three amino acid positions (11, 71 and 74) in HLA-DRbeta1 and single-amino-acid polymorphisms in HLA-B (position 9) and HLA-DPbeta1 (position 9), all located in peptide-binding grooves, almost completely explain MHC association to rheumatoid arthritis ...
      Title: Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.
    4. variants previously associated with chronic hepatitis B are also strongly associated with mRNA expression of HLA-DPA1 and HLA-DPB1, suggesting that expression of these genes is important in control of HBV.
      Title: Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver.
    5. Characterization of 236 novel alleles at the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci
      Title: Characterization of 236 novel alleles at the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci from China Marrow Donor Program.
    6. The HLA-DPB1*09 and DPB1*1701 alleles might increase the susceptibility to Takayasu arteritis (TA), and the individuals possessing DPB1*1701 had the earlier onset age of the disease.
      Title: Association of susceptibility to Takayasu arteritis in Chinese Han patients with HLA-DPB1.
    7. we established several CD4 T-cell clones that recognized a peptide that is embedded within Melan-A/MART-121-50, in a HLA-DPB1*0501 restricted manner
      Title: Identification of an HLA-DPB1*0501 restricted Melan-A/MART-1 epitope recognized by CD4+ T lymphocytes: prevalence for immunotherapy in Asian populations.
    8. HLA-DPB1 carriage and high exposure to beryllium appear to contribute individually to the development of Beryllium sensitisation and chronic beryllium disease
      Title: Exposure and genetics increase risk of beryllium sensitisation and chronic beryllium disease in the nuclear weapons industry.
    9. genetic variants in the HLA-DPA1 and HLA-DPB1 locus are associated with the risk of pediatric asthma in Asian populations.
      Title: Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
    10. four loci showed the strongest associations with RA (P<0.005): ZNF391, OR2H1, C6orf26-RDBP and HLA-DPB1-COL11A2.
      Title: HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort.
    Submit: New GeneRIF Correction See all (79)
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

    A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

    Beryllium disease, chronic, susceptibility to

    Genome-wide association study identifies susceptibility loci for IgA nephropathy.

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    HIV-1 protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env HIV envelope protein gp120 can specifically inhibit CD4-dependent class II MHC-restricted T cell response to Ag PubMed
    env Amino acid residues 42-49 in the V1 region of CD4 are involved in the interaction between HIV-1 gp120 and class II major histocompatibility complex molecules PubMed
    Envelope surface glycoprotein gp160, precursor env Processing of HIV-1 gp160 to gp120 and gp41 is necessary for the association of HIV-1 envelope glycoproteins with class II MHC PubMed
    Envelope transmembrane glycoprotein gp41 env Soluble HIV-1 gp41 can selectively enhance MHC class I and II expression on human B cells, but does not increase expression of other cell surface antigens such as CD21 and CD54 (ICAM-1) PubMed
    env Soluble HIV-1 gp41 enhancement effects on MHC class I and II antigen expression can be inhibited by soluble gp41-binding proteins of 45, 49 and 62 kD from human B cells PubMed
    env A 43-amino-acid sequence between amino acids 708 and 750 in the HIV-1 gp41(TM) cytoplasmic tail is required for efficient incorporation of HLA class II proteins into virions PubMed
    Tat tat HIV-1 Tat downregulates expression of MHC class II genes in antigen-presenting cells (APC) by inhibiting the transactivator of MHC class II genes, CIITA PubMed

    Go to the HIV-1, Human Protein Interaction Database

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    P04440 P04233 CD74    HPRD  PubMed  
    P04440 P20036 HLA-DPA1    HPRD  PubMed  
    BioGRID:109360 BioGRID:112019 ROBO2    BioGRID  PubMed Two-hybrid 
    BioGRID:109360 BioGRID:121400 RTN4    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Genotypes

    Pathways from BioSystems

    • Adaptive Immune System, organism-specific biosystem (from REACTOME)
      Adaptive Immune System, organism-specific biosystemAdaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with...
    • Allograft rejection, organism-specific biosystem (from KEGG)
      Allograft rejection, organism-specific biosystemAllograft rejection is the consequence of the recipient's alloimmune response to nonself antigens expressed by donor tissues. After transplantation of organ allografts, there are two pathways of anti...
    • Allograft rejection, conserved biosystem (from KEGG)
      Allograft rejection, conserved biosystemAllograft rejection is the consequence of the recipient's alloimmune response to nonself antigens expressed by donor tissues. After transplantation of organ allografts, there are two pathways of anti...
    • Antigen processing and presentation, organism-specific biosystem (from KEGG)
      Antigen processing and presentation, organism-specific biosystem
      Antigen processing and presentation
    • Antigen processing and presentation, conserved biosystem (from KEGG)
      Antigen processing and presentation, conserved biosystem
      Antigen processing and presentation
    • Asthma, organism-specific biosystem (from KEGG)
      Asthma, organism-specific biosystemAsthma is a complex syndrome with many clinical phenotypes in both adults and children. Its major characteristics include a variable degree of airflow obstruction, bronchial hyperresponsiveness, and ...
    • Asthma, conserved biosystem (from KEGG)
      Asthma, conserved biosystemAsthma is a complex syndrome with many clinical phenotypes in both adults and children. Its major characteristics include a variable degree of airflow obstruction, bronchial hyperresponsiveness, and ...
    • Autoimmune thyroid disease, organism-specific biosystem (from KEGG)
      Autoimmune thyroid disease, organism-specific biosystemThe classification of autoimmune throid disease (AITD) includes Hashimoto's thyroiditis (HT) or chronic autoimmune thyroiditis and its variants, Graves' disease (GD) and autoimmune atrophic thyroidi...
    • Autoimmune thyroid disease, conserved biosystem (from KEGG)
      Autoimmune thyroid disease, conserved biosystemThe classification of autoimmune throid disease (AITD) includes Hashimoto's thyroiditis (HT) or chronic autoimmune thyroiditis and its variants, Graves' disease (GD) and autoimmune atrophic thyroidi...
    • Cell adhesion molecules (CAMs), organism-specific biosystem (from KEGG)
      Cell adhesion molecules (CAMs), organism-specific biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
    • Cell adhesion molecules (CAMs), conserved biosystem (from KEGG)
      Cell adhesion molecules (CAMs), conserved biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
    • Costimulation by the CD28 family, organism-specific biosystem (from REACTOME)
      Costimulation by the CD28 family, organism-specific biosystemOptimal activation of T-lymphocytes requires at least two signals. A primary one is delivered by the T-cell receptor (TCR) complex after antigen recognition and additional costimulatory signals are d...
    • Cytokine Signaling in Immune system, organism-specific biosystem (from REACTOME)
      Cytokine Signaling in Immune system, organism-specific biosystemCytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concen...
    • Downstream TCR signaling, organism-specific biosystem (from REACTOME)
      Downstream TCR signaling, organism-specific biosystemChanges in gene expression are required for the T cell to gain full proliferative competence and to produce effector cytokines. Three transcription factors in particular have been found to play a key...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Generation of second messenger molecules, organism-specific biosystem (from REACTOME)
      Generation of second messenger molecules, organism-specific biosystemIn addition to serving as a scaffold via auto-phosphorylation, ZAP-70 also phosphorylates a restricted set of substrates following TCR stimulation - including LAT and SLP-76. These substrates have be...
    • Graft-versus-host disease, organism-specific biosystem (from KEGG)
      Graft-versus-host disease, organism-specific biosystemGraft-versus-host disease (GVHD) is a lethal complication of allogeneic hematopoietic stem cell transplantation (HSCT) where immunocompetent donor T cells attack the genetically disparate host cells....
    • Graft-versus-host disease, conserved biosystem (from KEGG)
      Graft-versus-host disease, conserved biosystemGraft-versus-host disease (GVHD) is a lethal complication of allogeneic hematopoietic stem cell transplantation (HSCT) where immunocompetent donor T cells attack the genetically disparate host cells....
    • HTLV-I infection, organism-specific biosystem (from KEGG)
      HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • HTLV-I infection, conserved biosystem (from KEGG)
      HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • Herpes simplex infection, organism-specific biosystem (from KEGG)
      Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Herpes simplex infection, conserved biosystem (from KEGG)
      Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Immune System, organism-specific biosystem (from REACTOME)
      Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
    • Influenza A, organism-specific biosystem (from KEGG)
      Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Influenza A, conserved biosystem (from KEGG)
      Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Interferon Signaling, organism-specific biosystem (from REACTOME)
      Interferon Signaling, organism-specific biosystemInterferons (IFNs) are cytokines that play a central role in initiating immune responses, especially antiviral and antitumor effects. There are three types of IFNs:Type I (IFN-alpha, -beta and others...
    • Interferon gamma signaling, organism-specific biosystem (from REACTOME)
      Interferon gamma signaling, organism-specific biosystemInterferon-gamma (IFN-gamma) belongs to the type II interferon family and is secreted by activated immune cells-primarily T and NK cells, but also B-cells and APC. INFG exerts its effect on cells by ...
    • Intestinal immune network for IgA production, organism-specific biosystem (from KEGG)
      Intestinal immune network for IgA production, organism-specific biosystemThe intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great amounts of noninflammatory immunoglobulin A (IgA) antibodies tha...
    • Intestinal immune network for IgA production, conserved biosystem (from KEGG)
      Intestinal immune network for IgA production, conserved biosystemThe intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great amounts of noninflammatory immunoglobulin A (IgA) antibodies tha...
    • Leishmaniasis, organism-specific biosystem (from KEGG)
      Leishmaniasis, organism-specific biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
    • Leishmaniasis, conserved biosystem (from KEGG)
      Leishmaniasis, conserved biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
    • PD-1 signaling, organism-specific biosystem (from REACTOME)
      PD-1 signaling, organism-specific biosystemThe Programmed cell death protein 1 (PD-1) is one of the negative regulators of TCR signaling. PD-1 may exert its effects on cell differentiation and survival directly by inhibiting early activation ...
    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phosphorylation of CD3 and TCR zeta chains, organism-specific biosystem (from REACTOME)
      Phosphorylation of CD3 and TCR zeta chains, organism-specific biosystemPrior to T cell receptor (TCR) stimulation, CD4/CD8 associated Lck remains seperated from the TCR and is maintained in an inactive state by the action of Csk. Csk phosphorylates the negative regulato...
    • Rheumatoid arthritis, organism-specific biosystem (from KEGG)
      Rheumatoid arthritis, organism-specific biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
    • Rheumatoid arthritis, conserved biosystem (from KEGG)
      Rheumatoid arthritis, conserved biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
    • Staphylococcus aureus infection, organism-specific biosystem (from KEGG)
      Staphylococcus aureus infection, organism-specific biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
    • Staphylococcus aureus infection, conserved biosystem (from KEGG)
      Staphylococcus aureus infection, conserved biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
    • Systemic lupus erythematosus, organism-specific biosystem (from KEGG)
      Systemic lupus erythematosus, organism-specific biosystemSystemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and cert...
    • Systemic lupus erythematosus, conserved biosystem (from KEGG)
      Systemic lupus erythematosus, conserved biosystemSystemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and cert...
    • TCR signaling, organism-specific biosystem (from REACTOME)
      TCR signaling, organism-specific biosystemThe TCR is a multisubunit complex that consists of clonotypic alpha/beta chains noncovalently associated with the invariant CD3 delta/epsilon/gamma and TCR zeta chains. T cell activation by antigen p...
    • Toxoplasmosis, organism-specific biosystem (from KEGG)
      Toxoplasmosis, organism-specific biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Toxoplasmosis, conserved biosystem (from KEGG)
      Toxoplasmosis, conserved biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Translocation of ZAP-70 to Immunological synapse, organism-specific biosystem (from REACTOME)
      Translocation of ZAP-70 to Immunological synapse, organism-specific biosystemThe dual phosphorylated ITAMs recruit Syk kinase ZAP-70 via their tandem SH2 domains (step 4). ZAP-70 subsequently undergoes phosphorylation on multiple tyrosine residues for further activation. ZAP-...
    • Tuberculosis, organism-specific biosystem (from KEGG)
      Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Tuberculosis, conserved biosystem (from KEGG)
      Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Type I diabetes mellitus, organism-specific biosystem (from KEGG)
      Type I diabetes mellitus, organism-specific biosystemType I diabetes mellitus is a disease that results from autoimmune destruction of the insulin-producing beta-cells. Certain beta-cell proteins act as autoantigens after being processed by antigen-pre...
    • Type I diabetes mellitus, conserved biosystem (from KEGG)
      Type I diabetes mellitus, conserved biosystemType I diabetes mellitus is a disease that results from autoimmune destruction of the insulin-producing beta-cells. Certain beta-cell proteins act as autoantigens after being processed by antigen-pre...
    • Viral myocarditis, organism-specific biosystem (from KEGG)
      Viral myocarditis, organism-specific biosystemMyocarditis is a cardiac disease associated with inflammation and injury of the myocardium. It results from various etiologies, both noninfectious and infectious, but coxsackievirus B3 (CVB3) is stil...

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    T cell costimulation TAS
    Traceable Author Statement
    more info
    		  
    T cell receptor signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytokine-mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    interferon-gamma-mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane TAS
    Traceable Author Statement
    more info
    		  
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    General protein information

    Preferred Names
    HLA class II histocompatibility antigen, DP beta 1 chain
    Names
    HLA class II histocompatibility antigen, DP beta 1 chain
    MHC HLA DPB1
    HLA DP14-beta chain
    MHC class II HLA-DRB1
    class II HLA beta chain
    MHC class II HLA-DP-beta
    MHC class II antigen DPB1
    MHC class II HLA-DP-beta-1
    MHC class II antigen DPbeta1
    MHC class II antigen beta chain
    beta1 domain MHC class II HLA DPB
    MHC class II antigen DP beta 1 chain
    HLA-DP histocompatibility type, beta-1 subunit
    HLA class II histocompatibility antigen, DP(W4) beta chain
    major histocompatibility complex class II HLA DPB1 protein
    major histocompatibility complex class II antigen beta chain
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_002121.5 → NP_002112.3  HLA class II histocompatibility antigen, DP beta 1 chain precursor

      Status: REVIEWED

      Source sequence(s)
      AL645931, BP213121, M28202
      Consensus CDS
      CCDS4765.1
      UniProtKB/Swiss-Prot
      P04440
      Related
      ENSP00000408146, OTTHUMP00000029093, ENST00000418931, OTTHUMT00000076106
      Conserved Domains (2) summary
      cd05766
      Location:124 – 217
      Blast Score: 413
      IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain
      cl03042
      Location:43 – 113
      Blast Score: 361
      MHC_II_beta; Class II histocompatibility antigen, beta domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000006.11 Reference GRCh37.p5 Primary Assembly

      Range
      33043703..33057473
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_1

    Genomic

    1. NT_167244.1 Reference GRCh37.p5 ALT_REF_LOCI_1

      Range
      4330504..4344264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.2 Reference GRCh37.p5 ALT_REF_LOCI_2

      Range
      4487883..4501576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_3

    Genomic

    1. NT_167245.1 Reference GRCh37.p5 ALT_REF_LOCI_3

      Range
      4325042..4338804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_4

    Genomic

    1. NT_167246.1 Reference GRCh37.p5 ALT_REF_LOCI_4

      Range
      4501243..4515019
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_5

    Genomic

    1. NT_167247.1 Reference GRCh37.p5 ALT_REF_LOCI_5

      Range
      4380558..4394318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_6

    Genomic

    1. NT_167248.1 Reference GRCh37.p5 ALT_REF_LOCI_6

      Range
      4276154..4289926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_7

    Genomic

    1. NT_167249.1 Reference GRCh37.p5 ALT_REF_LOCI_7

      Range
      4524207..4537977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000138.1 Alternate HuRef

      Range
      32786143..32799913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AB247517.1 BAE78492.1
    genomic AF041252.1 AAD02200.1
    genomic AF074845.1 AAD39682.1
    genomic AF074846.1 AAD39683.1
    genomic AF077015.1 AAC26835.1
    genomic AF180970.1 AAK58508.1
    genomic AF184168.1 AAF16938.1
    genomic AF211979.1 AAF32279.1
    genomic AF234538.1 AAF44659.1
    genomic AF280405.1 AAK00264.1
    genomic AF288354.1 AAG30143.1
    genomic AF288355.1 AAG30144.1
    genomic AF326565.1 AAK01673.1
    genomic AF335225.1 AAK20867.1
    genomic AF335226.1 AAK20868.1
    genomic AF335227.1 AAK20869.1
    genomic AF335228.1 AAK20870.1
    genomic AF335229.1 AAK20871.1
    genomic AF336222.1 AAK25777.1
    genomic AF336223.1 AAK25778.1
    genomic AF336224.1 AAK25779.1
    genomic AF336225.1 AAK25780.1
    genomic AF336226.1 AAK25781.1
    genomic AF336227.1 AAK25782.1
    genomic AF336228.1 AAK25783.1
    genomic AF336229.1 AAK25784.1
    genomic AF336230.1 AAK25785.1
    genomic AF336231.1 AAK25786.1
    genomic AF372451.1 AAK54754.1
    genomic AF372452.1 AAK54755.1
    genomic AF462072.2 AAL68647.2
    genomic AF489518.1 AAL92172.1
    genomic AF492636.1 AAO84761.1
    genomic AF492637.1 AAO84762.1
    genomic AF492638.1 AAO84763.1
    genomic AF492639.1 AAO84764.1
    genomic AF492640.1 AAO84765.1
    genomic AF492641.1 AAO84766.1
    genomic AF492642.1 AAO84767.1
    genomic AF492643.1 AAO84768.1
    genomic AF517128.1 AAM62425.1
    genomic AF536241.1 AAN33050.1
    genomic AF549409.1 AAQ12563.1
    genomic AF549410.1 AAQ12564.1
    genomic AJ238005.1 CAC12865.1
    genomic AJ245640.1 CAB53016.1
    genomic AJ271373.2 CAB70605.2
    genomic AJ292074.1 CAC27995.1
    genomic AJ297820.1 CAC14048.1
    genomic AJ514871.1 CAD55852.1
    genomic AJ563603.1 CAD91639.1
    genomic AJ563604.1 CAD91640.1
    genomic AJ581676.1 CAE46432.1
    genomic AJ810847.1 CAH18733.1
    genomic AL645931.7 (83865..97631) None
    genomic AL805913.4 CAI18551.1
      CAI18552.1
      CAM25765.1
      CAM25766.1
    genomic AL805913.4 CAI18551.1
      CAI18552.1
      CAM25765.1
      CAM25766.1
    genomic AL845446.7 CAI95555.1
    genomic AM039828.1 CAJ01690.1
    genomic AM158320.1 CAJ43602.1
    genomic AM408787.1 CAL64063.1
    genomic AY029777.1 AAK40344.1
    genomic AY033075.1 AAK51161.1
    genomic AY335522.1 AAR01826.1
    genomic AY335523.1 AAR01828.1
    genomic AY335524.1 AAR01830.1
    genomic AY335525.1 AAR01832.1
    genomic AY335526.1 AAR01834.1
    genomic AY335527.1 AAR01836.1
    genomic AY335528.1 AAR01838.1
    genomic AY335529.1 AAR01840.1
    genomic AY335530.1 AAR01842.1
    genomic AY335531.1 AAR01844.1
    genomic AY335532.1 AAR01846.1
    genomic AY335533.1 AAR01848.1
    genomic AY335534.1 AAR01850.1
    genomic AY335535.1 AAR01852.1
    genomic AY335536.1 AAR01854.1
    genomic AY335537.1 AAR01856.1
    genomic AY335538.1 AAR01858.1
    genomic AY335539.1 AAR01860.1
    genomic AY335540.1 AAR01862.1
    genomic AY335541.1 AAR01864.1
    genomic AY335542.1 AAR01866.1
    genomic AY335543.1 AAR01868.1
    genomic AY335544.1 AAR01870.1
    genomic AY374100.1 AAR21105.1
    genomic AY375772.1 AAQ88052.1
    genomic AY375774.1 AAQ88055.1
    genomic AY375776.1 AAQ88053.1
    genomic AY375779.1 AAQ88050.1
    genomic AY375782.1 AAQ88056.1
    genomic AY375783.1 AAQ88051.1
    genomic AY375784.1 AAQ88060.1
    genomic AY375785.1 AAQ88048.1
    genomic AY375788.1 AAQ88049.1
    genomic AY375790.1 AAQ88054.1
    genomic AY375796.1 AAQ88090.1
    genomic AY375797.1 AAQ88091.1
    genomic AY375800.1 AAQ88094.1
    genomic AY375804.1 AAQ88063.1
    genomic AY375805.1 AAQ88064.1
    genomic AY375806.1 AAQ88065.1
    genomic AY375807.1 AAQ88066.1
    genomic AY375808.1 AAQ88067.1
    genomic AY375809.1 AAQ88068.1
    genomic AY375810.1 AAQ88069.1
    genomic AY375811.1 AAQ88070.1
    genomic AY375812.1 AAQ88071.1
    genomic AY375813.1 AAQ88072.1
    genomic AY375814.1 AAQ88073.1
    genomic AY375815.1 AAQ88074.1
    genomic AY375816.1 AAQ88075.1
    genomic AY375817.1 AAQ88076.1
    genomic AY375818.1 AAQ88077.1
    genomic AY375819.1 AAQ88078.1
    genomic AY375820.1 AAQ88079.1
    genomic AY375821.1 AAQ88080.1
    genomic AY375822.1 AAQ88081.1
    genomic AY375823.1 AAQ88082.1
    genomic AY375824.1 AAQ88083.1
    genomic AY375826.1 AAQ88085.1
    genomic AY425707.1 AAR29060.1
    genomic AY572830.1 AAS77869.1
    genomic AY582141.1 AAT81151.1
    genomic AY618897.1 AAT40308.1
    genomic AY823995.1 AAW79272.1
    genomic AY855160.1 AAW33682.1
    genomic AY855161.1 AAW33683.1
    genomic BX120009.10 CAM25984.1
      CAM25985.1
    genomic CH471081.1 EAX03672.1
      EAX03673.1
      EAX03674.1
      EAX03675.1
    genomic CR759795.4 (78340..89546) None
    genomic CR759904.5 (56384..67590) None
    genomic CR762479.5 CAQ10348.1
      CAQ10349.1
    genomic CR847849.5 (20358..31580) None
    genomic D10478.1 BAA01281.1
    genomic D10479.1 BAA01282.1
    genomic D10834.1 BAA01614.1
    genomic D10882.1 BAA01704.1
    genomic D13174.1 BAA02465.1
    genomic D14344.1 BAA03278.1
    genomic D28809.1 BAA05970.1
    genomic DQ089022.1 AAY98352.1
    genomic DQ100371.1 AAZ13612.1
    genomic DQ148299.1 ABA33892.1
    genomic DQ206450.1 ABB17974.1
    genomic DQ282119.1 ABB91805.1
    genomic DQ386161.1 ABD36812.1
    genomic DQ485789.1 ABF47047.1
    genomic K03014.1 AAA36310.1
    genomic L07768.1 AAA59690.1
    genomic L09236.1 AAA16928.1
    genomic L17310.1 AAA53479.1
    genomic L17311.1 AAA53480.1
    genomic L17313.1 AAA53481.1
    genomic L17314.1 AAA53482.1
    genomic L22076.1 AAA53476.1
    genomic L22077.1 AAA53477.1
    genomic L23400.1 AAA58441.1
    genomic L29174.1 AAA59843.1
    genomic M23675.1 AAA59740.1
    genomic M23676.1 AAA59741.1
    genomic M23677.1 AAA59742.1
    genomic M23678.1 AAA59743.1
    genomic M23679.1 AAA59744.1
    genomic M23680.1 AAA59745.1
    genomic M23681.1 AAA59746.1
    genomic M23682.1 AAA59747.1
    genomic M23683.1 AAA59748.1
    genomic M23685.1 AAA59750.1
    genomic M23686.1 AAA59751.1
    genomic M23687.1 AAA59752.1
    genomic M23906.1 AAA59828.1
    genomic M23907.1 AAA59828.1
    genomic M23908.1 AAA59828.1
    genomic M31778.1 AAA36255.1
    genomic M31780.1 AAA36257.1
    genomic M31781.1 AAA36258.1
    genomic M58608.1 AAA59753.1
    genomic M62326.1 AAA59719.1
    genomic M62327.1 AAA59720.1
    genomic M62328.1 AAA59721.1
    genomic M62329.1 AAA59722.1
    genomic M62330.1 AAA59723.1
    genomic M62331.1 AAA59724.1
    genomic M62332.1 AAA59725.1
    genomic M62333.1 AAA59726.1
    genomic M62334.1 AAA59727.1
    genomic M62335.1 AAA59728.1
    genomic M62337.1 AAA59730.1
    genomic M62338.1 AAA59731.1
    genomic M62340.1 AAA59733.1
    genomic M62341.1 AAA59734.1
    genomic M62342.1 AAA59735.1
    genomic M62343.1 AAA59736.1
    genomic M62344.1 AAA59737.1
    genomic M63508.1 AAA59738.1
    genomic M83912.1 AAA36266.1
    genomic M83913.1 AAA36265.1
    genomic M83914.1 AAA36264.1
    genomic M83915.1 AAA36259.1
    genomic M83916.1 AAA36260.1
    genomic M83917.1 AAA36261.1
    genomic M83918.1 AAA36262.1
    genomic M83919.1 AAA36263.1
    genomic M84014.1 AAA59650.1
    genomic M85222.1 AAA52663.1
    genomic M85223.1 AAA35994.1
    genomic S53170.1 AAB24928.1
    genomic S70106.1 AAB29915.1
    genomic S72495.1 AAB32181.1
    genomic U22311.1 AAB60413.1
    genomic U22312.1 AAB60414.1
    genomic U22313.1 AAB17108.1
    genomic U29534.1 AAB52511.1
    genomic U34033.1 AAA81335.1
    genomic U59437.1 AAD09481.1
    genomic U59438.1 AAD09482.1
    genomic U59439.1 AAD09483.1
    genomic U59440.1 AAD09484.1
    genomic U59441.1 AAD09485.1
    genomic U59442.1 AAD09486.1
    genomic X02228.1 CAA26147.1
    genomic X03022.1 CAA26823.1
    genomic X03023.1 CAE82008.1
    genomic X03024.1 CAE82007.1
    genomic X03025.1 CAE82037.1
    genomic X03026.1 CAE82042.1
    genomic X03027.1 CAE82043.1
    genomic X03028.1 CAE82073.1
    genomic X03100.1 CAA26886.1
    genomic X80331.1 CAA56581.1
    genomic X80752.1 CAA56728.1
    genomic X82123.1 CAA57635.1
    genomic X96986.1 CAA65710.2
    genomic X97406.1 CAA66059.1
    genomic Y08862.1 CAA70086.1
    genomic Y09327.1 CAA70507.1
    genomic Y13900.1 CAA74199.1
    genomic Y14230.1 CAA74608.1
    genomic Y16095.1 CAA76060.1
    genomic Y18498.1 CAC12860.1
    genomic Z92523.1 CAB06822.1
    mRNA AB208978.1 BAD92215.1
    mRNA AK291986.1 BAF84675.1
    mRNA AK301322.1 BAG62871.1
    mRNA AK303153.1 BAG64256.1
    mRNA AK313305.1 BAG36110.1
    mRNA AY656678.1 AAV71025.1
    mRNA AY656679.1 AAV71026.1
    mRNA AY656680.1 AAV71027.1
    mRNA AY804132.1 AAW78737.1
    mRNA AY804133.1 AAW78738.1
    mRNA AY804134.1 AAW78739.1
    mRNA AY804135.1 AAW78740.1
    mRNA AY804136.1 AAW78741.1
    mRNA AY804137.1 AAW78742.1
    mRNA AY804138.1 AAW78743.1
    mRNA AY804139.1 AAW78744.1
    mRNA AY804140.1 AAW78745.1
    mRNA AY804141.1 AAW78746.1
    mRNA AY804142.1 AAW78747.1
    mRNA AY804143.1 AAW78748.1
    mRNA AY831401.1 AAW80919.1
    mRNA AY831402.1 AAW80920.1
    mRNA AY831403.1 AAW80921.1
    mRNA AY831404.1 AAW80922.1
    mRNA BC007963.2 AAH07963.1
    mRNA BC013184.1 AAH13184.1
    mRNA BC015000.1 AAH15000.1
    mRNA BP213121.1 None
    mRNA BT019780.1 AAV38583.1
    mRNA DQ284441.1 ABC66207.1
    mRNA GQ891549.1 ACX50636.1
    mRNA J03041.1 AAA35993.1
    mRNA K00409.1 AAA36312.1
    mRNA K01615.1 AAA36313.1
    mRNA L29173.1 AAA36311.1
    mRNA M21886.1 AAA59739.1
    mRNA M28200.1 AAA53195.1
    mRNA M28201.1 AAA53196.1
    mRNA M28202.1 AAA53197.1
    mRNA M57466.1 AAA63221.1
    mRNA M83664.1 AAA59837.1
    mRNA S66883.1 AAB28826.1
    mRNA X00532.1 CAA25210.1
    mRNA X01426.1 CAA25672.1
    mRNA X03067.1 CAA26871.1
    other-genetic DQ891050.2 ABM81976.1
    other-genetic DQ894229.2 ABM85155.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O19628 GenPept UniProtKB/TrEMBL:O19628
    O19686 GenPept UniProtKB/TrEMBL:O19686
    O19699 GenPept UniProtKB/TrEMBL:O19699
    O19701 GenPept UniProtKB/TrEMBL:O19701
    P04440.1 GenPept UniProtKB/Swiss-Prot:P04440
    Q05853 GenPept UniProtKB/TrEMBL:Q05853
    Q14465 GenPept UniProtKB/TrEMBL:Q14465
    Q29670 GenPept UniProtKB/TrEMBL:Q29670
    Q29683 GenPept UniProtKB/TrEMBL:Q29683
    Q29773 GenPept UniProtKB/TrEMBL:Q29773
    Q29774 GenPept UniProtKB/TrEMBL:Q29774
    Q29777 GenPept UniProtKB/TrEMBL:Q29777
    Q29780 GenPept UniProtKB/TrEMBL:Q29780
    Q29860 GenPept UniProtKB/TrEMBL:Q29860
    Q29881 GenPept UniProtKB/TrEMBL:Q29881
    Q29956 GenPept UniProtKB/TrEMBL:Q29956
    Q29964 GenPept UniProtKB/TrEMBL:Q29964
    Q2PZR0 GenPept UniProtKB/TrEMBL:Q2PZR0
    Q2UVJ2 GenPept UniProtKB/TrEMBL:Q2UVJ2
    Q30012 GenPept UniProtKB/TrEMBL:Q30012
    Q30013 GenPept UniProtKB/TrEMBL:Q30013
    Q30014 GenPept UniProtKB/TrEMBL:Q30014
    Q30016 GenPept UniProtKB/TrEMBL:Q30016
    Q30017 GenPept UniProtKB/TrEMBL:Q30017
    Q30018 GenPept UniProtKB/TrEMBL:Q30018
    Q30019 GenPept UniProtKB/TrEMBL:Q30019
    Q30020 GenPept UniProtKB/TrEMBL:Q30020
    Q30021 GenPept UniProtKB/TrEMBL:Q30021
    Q30022 GenPept UniProtKB/TrEMBL:Q30022
    Q30023 GenPept UniProtKB/TrEMBL:Q30023
    Q30024 GenPept UniProtKB/TrEMBL:Q30024
    Q30025 GenPept UniProtKB/TrEMBL:Q30025
    Q30026 GenPept UniProtKB/TrEMBL:Q30026
    Q30027 GenPept UniProtKB/TrEMBL:Q30027
    Q30028 GenPept UniProtKB/TrEMBL:Q30028
    Q30029 GenPept UniProtKB/TrEMBL:Q30029
    Q30030 GenPept UniProtKB/TrEMBL:Q30030
    Q30035 GenPept UniProtKB/TrEMBL:Q30035
    Q30036 GenPept UniProtKB/TrEMBL:Q30036
    Q30037 GenPept UniProtKB/TrEMBL:Q30037
    Q30038 GenPept UniProtKB/TrEMBL:Q30038
    Q30039 GenPept UniProtKB/TrEMBL:Q30039
    Q30040 GenPept UniProtKB/TrEMBL:Q30040
    Q30041 GenPept UniProtKB/TrEMBL:Q30041
    Q30042 GenPept UniProtKB/TrEMBL:Q30042
    Q30043 GenPept UniProtKB/TrEMBL:Q30043
    Q30044 GenPept UniProtKB/TrEMBL:Q30044
    Q30045 GenPept UniProtKB/TrEMBL:Q30045
    Q30046 GenPept UniProtKB/TrEMBL:Q30046
    Q30047 GenPept UniProtKB/TrEMBL:Q30047
    Q30048 GenPept UniProtKB/TrEMBL:Q30048
    Q30049 GenPept UniProtKB/TrEMBL:Q30049
    Q30056 GenPept UniProtKB/TrEMBL:Q30056
    Q30057 GenPept UniProtKB/TrEMBL:Q30057
    Q30058 GenPept UniProtKB/TrEMBL:Q30058
    Q30059 GenPept UniProtKB/TrEMBL:Q30059
    Q30060 GenPept UniProtKB/TrEMBL:Q30060
    Q30161 GenPept UniProtKB/TrEMBL:Q30161
    Q30180 GenPept UniProtKB/TrEMBL:Q30180
    Q30212 GenPept UniProtKB/TrEMBL:Q30212
    Q30214 GenPept UniProtKB/TrEMBL:Q30214
    Q30215 GenPept UniProtKB/TrEMBL:Q30215
    Q31619 GenPept UniProtKB/TrEMBL:Q31619
    Q49U28 GenPept UniProtKB/TrEMBL:Q49U28
    Q49U30 GenPept UniProtKB/TrEMBL:Q49U30
    Q49U32 GenPept UniProtKB/TrEMBL:Q49U32
    Q49U34 GenPept UniProtKB/TrEMBL:Q49U34
    Q49U36 GenPept UniProtKB/TrEMBL:Q49U36
    Q49U38 GenPept UniProtKB/TrEMBL:Q49U38
    Q49U40 GenPept UniProtKB/TrEMBL:Q49U40
    Q49U42 GenPept UniProtKB/TrEMBL:Q49U42
    Q49U44 GenPept UniProtKB/TrEMBL:Q49U44
    Q49U46 GenPept UniProtKB/TrEMBL:Q49U46
    Q49U48 GenPept UniProtKB/TrEMBL:Q49U48
    Q49U50 GenPept UniProtKB/TrEMBL:Q49U50
    Q49U52 GenPept UniProtKB/TrEMBL:Q49U52
    Q49U54 GenPept UniProtKB/TrEMBL:Q49U54
    Q49U56 GenPept UniProtKB/TrEMBL:Q49U56
    Q49U58 GenPept UniProtKB/TrEMBL:Q49U58
    Q49U60 GenPept UniProtKB/TrEMBL:Q49U60
    Q49U62 GenPept UniProtKB/TrEMBL:Q49U62
    Q49U64 GenPept UniProtKB/TrEMBL:Q49U64
    Q49U66 GenPept UniProtKB/TrEMBL:Q49U66
    Q49U68 GenPept UniProtKB/TrEMBL:Q49U68
    Q49U70 GenPept UniProtKB/TrEMBL:Q49U70
    Q49U72 GenPept UniProtKB/TrEMBL:Q49U72
    Q4F8G9 GenPept UniProtKB/TrEMBL:Q4F8G9
    Q59GY1 GenPept UniProtKB/TrEMBL:Q59GY1
    Q5EP48 GenPept UniProtKB/TrEMBL:Q5EP48
    Q5EP54 GenPept UniProtKB/TrEMBL:Q5EP54
    Q5SQ72 GenPept UniProtKB/TrEMBL:Q5SQ72
    Q5STN8 GenPept UniProtKB/TrEMBL:Q5STN8
    Q5V8U6 GenPept UniProtKB/TrEMBL:Q5V8U6
    Q67AN3 GenPept UniProtKB/TrEMBL:Q67AN3
    Q67AN4 GenPept UniProtKB/TrEMBL:Q67AN4
    Q67AN5 GenPept UniProtKB/TrEMBL:Q67AN5
    Q67AN6 GenPept UniProtKB/TrEMBL:Q67AN6
    Q67AN7 GenPept UniProtKB/TrEMBL:Q67AN7
    Q67AN8 GenPept UniProtKB/TrEMBL:Q67AN8
    Q67AN9 GenPept UniProtKB/TrEMBL:Q67AN9
    Q67AP0 GenPept UniProtKB/TrEMBL:Q67AP0
    Q67AP1 GenPept UniProtKB/TrEMBL:Q67AP1
    Q67AP2 GenPept UniProtKB/TrEMBL:Q67AP2
    Q67AP3 GenPept UniProtKB/TrEMBL:Q67AP3
    Q67AP4 GenPept UniProtKB/TrEMBL:Q67AP4
    Q67AP5 GenPept UniProtKB/TrEMBL:Q67AP5
    Q67AP6 GenPept UniProtKB/TrEMBL:Q67AP6
    Q67AP7 GenPept UniProtKB/TrEMBL:Q67AP7
    Q67AP8 GenPept UniProtKB/TrEMBL:Q67AP8
    Q67AP9 GenPept UniProtKB/TrEMBL:Q67AP9
    Q67AQ0 GenPept UniProtKB/TrEMBL:Q67AQ0
    Q67AQ1 GenPept UniProtKB/TrEMBL:Q67AQ1
    Q67AQ2 GenPept UniProtKB/TrEMBL:Q67AQ2
    Q67AQ3 GenPept UniProtKB/TrEMBL:Q67AQ3
    Q67AQ4 GenPept UniProtKB/TrEMBL:Q67AQ4
    Q67AQ5 GenPept UniProtKB/TrEMBL:Q67AQ5
    Q67AQ9 GenPept UniProtKB/TrEMBL:Q67AQ9
    Q67AR2 GenPept UniProtKB/TrEMBL:Q67AR2
    Q67AR3 GenPept UniProtKB/TrEMBL:Q67AR3
    Q67AR9 GenPept UniProtKB/TrEMBL:Q67AR9
    Q67AS1 GenPept UniProtKB/TrEMBL:Q67AS1
    Q67AS4 GenPept UniProtKB/TrEMBL:Q67AS4
    Q67AS5 GenPept UniProtKB/TrEMBL:Q67AS5
    Q67AS6 GenPept UniProtKB/TrEMBL:Q67AS6
    Q67AS7 GenPept UniProtKB/TrEMBL:Q67AS7
    Q67AT0 GenPept UniProtKB/TrEMBL:Q67AT0
    Q67AT3 GenPept UniProtKB/TrEMBL:Q67AT3
    Q67AT5 GenPept UniProtKB/TrEMBL:Q67AT5
    Q67AT7 GenPept UniProtKB/TrEMBL:Q67AT7
    Q68V11 GenPept UniProtKB/TrEMBL:Q68V11
    Q70GM2 GenPept UniProtKB/TrEMBL:Q70GM2
    Q7YQ09 GenPept UniProtKB/TrEMBL:Q7YQ09
    Q860Z4 GenPept UniProtKB/TrEMBL:Q860Z4
    Q860Z5 GenPept UniProtKB/TrEMBL:Q860Z5
    Q860Z6 GenPept UniProtKB/TrEMBL:Q860Z6
    Q860Z8 GenPept UniProtKB/TrEMBL:Q860Z8
    Q860Z9 GenPept UniProtKB/TrEMBL:Q860Z9
    Q861A0 GenPept UniProtKB/TrEMBL:Q861A0
    Q861A1 GenPept UniProtKB/TrEMBL:Q861A1
    Q8MH49 GenPept UniProtKB/TrEMBL:Q8MH49
    Q8SND2 GenPept UniProtKB/TrEMBL:Q8SND2
    Q95357 GenPept UniProtKB/TrEMBL:Q95357
    Q95HA4 GenPept UniProtKB/TrEMBL:Q95HA4
    Q95HC4 GenPept UniProtKB/TrEMBL:Q95HC4
    Q95HC5 GenPept UniProtKB/TrEMBL:Q95HC5
    Q95IH8 GenPept UniProtKB/TrEMBL:Q95IH8
    Q9BCQ3 GenPept UniProtKB/TrEMBL:Q9BCQ3
    Q9BCQ4 GenPept UniProtKB/TrEMBL:Q9BCQ4
    Q9BCQ5 GenPept UniProtKB/TrEMBL:Q9BCQ5
    Q9BCQ6 GenPept UniProtKB/TrEMBL:Q9BCQ6
    Q9BCQ7 GenPept UniProtKB/TrEMBL:Q9BCQ7
    Q9BCQ8 GenPept UniProtKB/TrEMBL:Q9BCQ8
    Q9BCQ9 GenPept UniProtKB/TrEMBL:Q9BCQ9
    Q9BCR0 GenPept UniProtKB/TrEMBL:Q9BCR0
    Q9BCR1 GenPept UniProtKB/TrEMBL:Q9BCR1
    Q9BCR2 GenPept UniProtKB/TrEMBL:Q9BCR2
    Q9BCS9 GenPept UniProtKB/TrEMBL:Q9BCS9
    Q9BCT0 GenPept UniProtKB/TrEMBL:Q9BCT0
    Q9BCT1 GenPept UniProtKB/TrEMBL:Q9BCT1
    Q9BCT2 GenPept UniProtKB/TrEMBL:Q9BCT2
    Q9BCT3 GenPept UniProtKB/TrEMBL:Q9BCT3
    Q9BD36 GenPept UniProtKB/TrEMBL:Q9BD36
    Q9BD44 GenPept UniProtKB/TrEMBL:Q9BD44
    Q9GJ40 GenPept UniProtKB/TrEMBL:Q9GJ40
    Q9MYE0 GenPept UniProtKB/TrEMBL:Q9MYE0
    Q9MYG7 GenPept UniProtKB/TrEMBL:Q9MYG7
    Q9TP05 GenPept UniProtKB/TrEMBL:Q9TP05
    Q9TQB2 GenPept UniProtKB/TrEMBL:Q9TQB2
    Q9UM37 GenPept UniProtKB/TrEMBL:Q9UM37
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