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Nfkb2 nuclear factor kappa B subunit 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 309452, updated on 17-May-2016
Official Symbol
Nfkb2provided by RGD
Official Full Name
nuclear factor kappa B subunit 2provided by RGD
Primary source
RGD:1307189
See related
Ensembl:ENSRNOG00000019311
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307189
Orthologs
Location:
1q54
Exon count:
23
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (266050633..266059266)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (273481574..273490218)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L19-like Neighboring gene uncharacterized LOC102551485 Neighboring gene pleckstrin and Sec7 domain containing Neighboring gene F-box and leucine-rich repeat protein 15

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Clone Names

  • MGC93816

Gene Ontology Provided by RGD

Process Evidence Code Pubs
I-kappaB kinase/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
NIK/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
NIK/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
aging IEP
Inferred from Expression Pattern
more info
PubMed 
extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix organization ISO
Inferred from Sequence Orthology
more info
 
follicular dendritic cell differentiation IEA
Inferred from Electronic Annotation
more info
 
follicular dendritic cell differentiation ISO
Inferred from Sequence Orthology
more info
 
germinal center formation IEA
Inferred from Electronic Annotation
more info
 
germinal center formation ISO
Inferred from Sequence Orthology
more info
 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
 
innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
response to cytokine IEP
Inferred from Expression Pattern
more info
PubMed 
response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
spleen development IEA
Inferred from Electronic Annotation
more info
 
spleen development ISO
Inferred from Sequence Orthology
more info
 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Bcl3/NF-kappaB2 complex IEA
Inferred from Electronic Annotation
more info
 
Bcl3/NF-kappaB2 complex ISO
Inferred from Sequence Orthology
more info
 
I-kappaB/NF-kappaB complex IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
nuclear factor NF-kappa-B p100 subunit
Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008349.1NP_001008350.1  nuclear factor NF-kappa-B p100 subunit

    See identical proteins and their annotated locations for NP_001008350.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085800
    UniProtKB/TrEMBL
    Q5U2Z4
    Related
    ENSRNOP00000026235, ENSRNOT00000026235
    Conserved Domains (6) summary
    cd07934
    Location:38221
    RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
    cd08798
    Location:773847
    Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
    cd00204
    Location:482619
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01177
    Location:228327
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    pfam12796
    Location:604697
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:487546
    Ank_4; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    266050633..266059266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231503.2XP_006231565.1  

    See identical proteins and their annotated locations for XP_006231565.1

    UniProtKB/TrEMBL
    Q5U2Z4
    Conserved Domains (6) summary
    cd07934
    Location:38221
    RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
    cd08798
    Location:773847
    Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
    cd00204
    Location:482619
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01177
    Location:228327
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    pfam12796
    Location:604697
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:487546
    Ank_4; Ankyrin repeats (many copies)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    240949824..240956078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)