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    Trim5 tripartite motif-containing 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308906, updated on 19-May-2013
    Official Symbol
    Trim5provided by RGD
    Official Full Name
    tripartite motif-containing 5provided by RGD
    Primary source
    RGD:1304579
    See related
    Ensembl:ENSRNOG00000017191
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304579
    Location :
    1q32
    Sequence :
    Chromosome: 1; NC_005100.3 (175586830..175603800, complement)
    See Trim5 in MapViewer

    Chromosome 1 - NC_005100.3Genomic Context describing neighboring genes Neighboring gene olfactory receptor pseudogene 151 Neighboring gene tripartite motif containing 6 Neighboring gene tripartite motif-containing 30 Neighboring gene similar to eukaryotic translation elongation factor 1 alpha 2

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    pattern recognition receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    activation of innate immune response ISO
    Inferred from Sequence Orthology
    more info
     
    pattern recognition receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of I-kappaB kinase/NF-kappaB cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NF-kappaB transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein K63-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein trimerization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of lipopolysaccharide-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic mRNA processing body ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    NOT nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    tripartite motif-containing protein 5
    Names
    tripartite motif-containing protein 5

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014023.1NP_001014045.1  tripartite motif-containing protein 5

      Status: PROVISIONAL

      Source sequence(s)
      BC078926
      UniProtKB/TrEMBL
      Q6AYT1
      Related
      ENSRNOP00000023099, ENSRNOT00000023100
      Conserved Domains (4) summary
      cd00021
      Location:96132
      Blast Score: 101
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd00162
      Location:1459
      Blast Score: 110
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      smart00449
      Location:350507
      Blast Score: 177
      SPRY; Domain in SPla and the RYanodine Receptor.
      pfam13923
      Location:1159
      Blast Score: 114
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: Build 5.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_5.0 Primary Assembly

    Genomic

    1. NC_005100.3 Reference Rnor_5.0 Primary Assembly

      Range
      175586830..175603800, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      156710957..156727926, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

      Supplemental Content

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