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Serpinc1 serpin family C member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304917, updated on 17-May-2016
Official Symbol
Serpinc1provided by RGD
Official Full Name
serpin family C member 1provided by RGD
Primary source
RGD:1307404
See related
Ensembl:ENSRNOG00000002783 Vega:OTTRNOG00000000179
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Orthologs
Location:
13q22
Exon count:
8
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (78806107..78820378)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (83700761..83715029)

Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene rCG43676-like Neighboring gene ring finger and CCCH-type domains 1 Neighboring gene BolA-like protein 2-like Neighboring gene zinc finger and BTB domain containing 37 Neighboring gene growth arrest specific 5

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
heparin binding IDA
Inferred from Direct Assay
more info
PubMed 
protease binding IEA
Inferred from Electronic Annotation
more info
 
protease binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
serine-type endopeptidase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acute inflammatory response to antigenic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
lactation IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
regulation of blood coagulation, intrinsic pathway IEA
Inferred from Electronic Annotation
more info
 
response to nutrient IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
blood microparticle IEA
Inferred from Electronic Annotation
more info
 
blood microparticle ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
antithrombin-III
Names
antithrombin III
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
serpin peptidase inhibitor, clade C (antithrombin), member 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012027.1NP_001012027.1  antithrombin-III precursor

    See identical proteins and their annotated locations for NP_001012027.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088467
    UniProtKB/TrEMBL
    Q5M7T5
    Related
    ENSRNOP00000003748, OTTRNOP00000000127, ENSRNOT00000003748, OTTRNOT00000000251
    Conserved Domains (1) summary
    cd02045
    Location:80459
    antithrombin-III_like; Antithrombin is a serine proteinase inhibitor (serpin) which controls the process of coagulation. It is the most important anticoagulant molecule in mammalian circulation systems, controlled by its interaction with the co-factor, heparin, which ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

    Range
    78806107..78820378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008769647.1XP_008767869.1  

    Conserved Domains (1) summary
    cd02045
    Location:79458
    antithrombin-III_like; Antithrombin is a serine proteinase inhibitor (serpin) which controls the process of coagulation. It is the most important anticoagulant molecule in mammalian circulation systems, controlled by its interaction with the co-factor, heparin, which ...

Alternate Rn_Celera

Genomic

  1. AC_000081.1 Alternate Rn_Celera

    Range
    73045672..73059940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)