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Mmp20 matrix metallopeptidase 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 300341, updated on 8-May-2016
Official Symbol
Mmp20provided by RGD
Official Full Name
matrix metallopeptidase 20provided by RGD
Primary source
RGD:1308730
See related
Ensembl:ENSRNOG00000021896
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Orthologs
Location:
8q11
Exon count:
11
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (5823147..5875351)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (5826487..5877399)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 8 Neighboring gene matrix metallopeptidase 27 Neighboring gene uncharacterized LOC102556477 Neighboring gene galectin-8 pseudogene Neighboring gene matrix metallopeptidase 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
metalloendopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
amelogenesis IEA
Inferred from Electronic Annotation
more info
 
amelogenesis ISO
Inferred from Sequence Orthology
more info
 
extracellular matrix disassembly IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix disassembly ISO
Inferred from Sequence Orthology
more info
 
protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
matrix metalloproteinase-20
Names
matrix metallopeptidase 20 (enamelysin)
matrix metalloproteinase 20 (enamelysin)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106800.1NP_001100270.1  matrix metalloproteinase-20 precursor

    See identical proteins and their annotated locations for NP_001100270.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473993
    UniProtKB/TrEMBL
    D3ZXD9
    Related
    ENSRNOP00000032003, ENSRNOT00000033306
    Conserved Domains (4) summary
    cd00094
    Location:292464
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:115270
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:115270
    Peptidase_M10; Matrixin
    pfam01471
    Location:3994
    PG_binding_1; Putative peptidoglycan binding domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    5823147..5875351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242487.2XP_006242549.1  

    Conserved Domains (4) summary
    cd00094
    Location:310482
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:133288
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:133288
    Peptidase_M10; Matrixin
    pfam01471
    Location:57112
    PG_binding_1; Putative peptidoglycan binding domain

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    6348869..6389463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)