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Bcar3 breast cancer anti-estrogen resistance 3 [ Mus musculus (house mouse) ]

Gene ID: 29815, updated on 8-May-2016
Official Symbol
Bcar3provided by MGI
Official Full Name
breast cancer anti-estrogen resistance 3provided by MGI
Primary source
MGI:MGI:1352501
See related
Ensembl:ENSMUSG00000028121 Vega:OTTMUSG00000052422
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AND-34; AI131758
Orthologs
Location:
3; 3 G3
Exon count:
14
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (122419780..122530189)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (122122698..122233101)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40139 Neighboring gene predicted gene, 40190 Neighboring gene microRNA 760 Neighboring gene predicted gene 4610 Neighboring gene predicted gene, 34349 Neighboring gene predicted gene, 34463 Neighboring gene microRNA 7657 Neighboring gene formin binding protein 1-like

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
lens morphogenesis in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of peptidyl-serine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
breast cancer anti-estrogen resistance protein 3
Names
p130Cas-binding protein AND-34

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013867.2NP_038895.1  breast cancer anti-estrogen resistance protein 3

    See identical proteins and their annotated locations for NP_038895.1

    Status: VALIDATED

    Source sequence(s)
    AC138720, AF179566
    Consensus CDS
    CCDS17810.1
    UniProtKB/Swiss-Prot
    Q9QZK2
    Related
    ENSMUSP00000029766, OTTMUSP00000070295, ENSMUST00000029766, OTTMUST00000131502
    Conserved Domains (2) summary
    cd10337
    Location:142276
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:539814
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    122419780..122530189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501558.2XP_006501621.1  

    Conserved Domains (2) summary
    cd10337
    Location:57191
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:454729
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
  2. XM_006501559.2XP_006501622.1  

    Conserved Domains (1) summary
    cl02485
    Location:190465
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    128819836..128930961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)