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Terf1 telomeric repeat binding factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297758, updated on 26-May-2016
Official Symbol
Terf1provided by RGD
Official Full Name
telomeric repeat binding factor 1provided by RGD
Primary source
RGD:1311574
See related
Ensembl:ENSRNOG00000007291
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Orthologs
Location:
5q11
Exon count:
10
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (2853455..2882728, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (2843150..2872418, complement)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene ribosomal protein S8-like Neighboring gene somatomedin B and thrombospondin, type 1 domain containing Neighboring gene hypothetical LOC100361352 Neighboring gene 60S ribosomal protein L7a-like Neighboring gene potassium voltage-gated channel subfamily B member 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC109063

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA binding, bending IEA
Inferred from Electronic Annotation
more info
 
DNA binding, bending ISO
Inferred from Sequence Orthology
more info
 
G-rich strand telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
 
double-stranded telomeric DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
double-stranded telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
 
microtubule binding IEA
Inferred from Electronic Annotation
more info
 
microtubule binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
telomerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to telomerase activity ISO
Inferred from Sequence Orthology
more info
 
telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 
ubiquitin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
G2/M transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
meiotic telomere clustering IEA
Inferred from Electronic Annotation
more info
 
meiotic telomere clustering ISO
Inferred from Sequence Orthology
more info
 
mitotic spindle assembly checkpoint IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle assembly checkpoint ISO
Inferred from Sequence Orthology
more info
 
negative regulation of DNA replication ISO
Inferred from Sequence Orthology
more info
 
negative regulation of establishment of RNA localization to telomere ISO
Inferred from Sequence Orthology
more info
 
negative regulation of establishment of protein localization to telomere ISO
Inferred from Sequence Orthology
more info
 
negative regulation of telomerase activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of telomerase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 
negative regulation of telomere maintenance via telomerase ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of microtubule polymerization IEA
Inferred from Electronic Annotation
more info
 
positive regulation of microtubule polymerization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitotic nuclear division ISO
Inferred from Sequence Orthology
more info
 
positive regulation of telosome assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of telosome assembly ISO
Inferred from Sequence Orthology
more info
 
protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
protein localization to chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
telomere maintenance ISO
Inferred from Sequence Orthology
more info
 
telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 
telomere maintenance via telomerase ISO
Inferred from Sequence Orthology
more info
 
telomeric loop formation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
nuclear chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
nuclear telomere cap complex IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear telomere cap complex ISO
Inferred from Sequence Orthology
more info
 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
spindle IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with spindle ISO
Inferred from Sequence Orthology
more info
 
telosome IEA
Inferred from Electronic Annotation
more info
 
telosome ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
telomeric repeat-binding factor 1
Names
telomeric repeat binding factor (NIMA-interacting) 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012464.1NP_001012482.1  telomeric repeat-binding factor 1

    See identical proteins and their annotated locations for NP_001012482.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089888
    UniProtKB/TrEMBL
    Q5EB98
    Related
    ENSRNOP00000043160, ENSRNOT00000049741
    Conserved Domains (3) summary
    smart00717
    Location:367414
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11660
    Location:370416
    SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
    cd00280
    Location:63251
    TRFH; Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability, ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    2853455..2882728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237729.2XP_006237791.1  

    Conserved Domains (3) summary
    smart00717
    Location:338385
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11660
    Location:341387
    SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
    cl02779
    Location:63222
    TRFH; Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability, ...

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    3039138..3068345 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)