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MACROD1 MACRO domain containing 1 [ Homo sapiens (human) ]

Gene ID: 28992, updated on 22-May-2016
Official Symbol
MACROD1provided by HGNC
Official Full Name
MACRO domain containing 1provided by HGNC
Primary source
HGNC:HGNC:29598
See related
Ensembl:ENSG00000133315 HPRD:17448; MIM:610400; Vega:OTTHUMG00000167843
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRP16
Orthologs
Location:
11q11
Exon count:
16
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (63998556..64166130, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (63766006..63933602, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 8A Neighboring gene uncharacterized LOC101927673 Neighboring gene OTU deubiquitinase, ubiquitin aldehyde binding 1 Neighboring gene uncharacterized LOC105369338 Neighboring gene fibronectin leucine rich transmembrane protein 1 Neighboring gene uncharacterized LOC105369339 Neighboring gene stress induced phosphoprotein 1

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
deacetylase activity IDA
Inferred from Direct Assay
more info
PubMed 
hydrolase activity, acting on glycosyl bonds IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to DNA damage stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein de-ADP-ribosylation IDA
Inferred from Direct Assay
more info
PubMed 
purine nucleoside metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
O-acetyl-ADP-ribose deacetylase MACROD1
Names
MACRO domain-containing protein 1
[Protein ADP-ribosylglutamate] hydrolase

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014067.3NP_054786.2  O-acetyl-ADP-ribose deacetylase MACROD1

    See identical proteins and their annotated locations for NP_054786.2

    Status: VALIDATED

    Source sequence(s)
    AF202922, BC003188, BQ637198
    Consensus CDS
    CCDS8056.1
    UniProtKB/Swiss-Prot
    Q9BQ69
    Related
    ENSP00000255681, OTTHUMP00000237037, ENST00000255681, OTTHUMT00000396570
    Conserved Domains (1) summary
    cd02908
    Location:153319
    Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    63998556..64166130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544970.1XP_011543272.1  

    Conserved Domains (1) summary
    cd02908
    Location:153309
    Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  2. XM_005273939.3XP_005273996.1  

    Conserved Domains (1) summary
    cd02908
    Location:153319
    Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
  3. XM_011544971.1XP_011543273.1  

    Conserved Domains (2) summary
    pfam00820
    Location:82176
    Lipoprotein_1; Borrelia lipoprotein
    cl00019
    Location:153176
    Macro; Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly ...
  4. XM_011544972.1XP_011543274.1  

    Conserved Domains (1) summary
    cl00019
    Location:153172
    Macro; Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly ...
  5. XM_006718521.2XP_006718584.1  

    Conserved Domains (1) summary
    cl00019
    Location:153178
    Macro; Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly ...
  6. XM_006718522.1XP_006718585.1  

    Conserved Domains (1) summary
    cl00019
    Location:153172
    Macro; Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly ...
  7. XM_005273940.1XP_005273997.1  

    Conserved Domains (1) summary
    cl00019
    Location:153172
    Macro; Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly ...

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    63649362..63816761 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)