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MAGEH1 MAGE family member H1 [ Homo sapiens (human) ]

Gene ID: 28986, updated on 8-May-2016
Official Symbol
MAGEH1provided by HGNC
Official Full Name
MAGE family member H1provided by HGNC
Primary source
HGNC:HGNC:24092
See related
Ensembl:ENSG00000187601 HPRD:06633; MIM:300548; Vega:OTTHUMG00000021655
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
APR1; APR-1; MAGEH
Summary
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]
Orthologs
Location:
Xp11.21
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (55452089..55453568)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (55478538..55479999)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene PAGE family member 5 pseudogene Neighboring gene PAGE family member 3 Neighboring gene microRNA 4536-1 Neighboring gene microRNA 4536-2 Neighboring gene uncharacterized LOC101928692 Neighboring gene ubiquitin specific peptidase 51 Neighboring gene MAGE family member E1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study of smoking behaviours among Bangladeshi adults.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
melanoma-associated antigen H1
Names
apoptosis-related protein 1
melanoma antigen family H, 1
melanoma antigen family H1
restin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_013248.1 RefSeqGene

    Range
    4985..6464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_014061.4NP_054780.2  melanoma-associated antigen H1

    See identical proteins and their annotated locations for NP_054780.2

    Status: REVIEWED

    Source sequence(s)
    AA634056, AF143235, AI191172, BI916425
    Consensus CDS
    CCDS14369.1
    UniProtKB/Swiss-Prot
    Q9H213
    Related
    ENSP00000343706, OTTHUMP00000023401, ENST00000342972, OTTHUMT00000056868
    Conserved Domains (1) summary
    pfam01454
    Location:88176
    MAGE; MAGE family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

    Range
    55452089..55453568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018934.2 Alternate CHM1_1.1

    Range
    55468667..55470146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)