C19orf53 chromosome 19 open reading frame 53 [Homo sapiens] - Gene

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Summary

Official Symbol: C19orf53provided by HGNC
Official Full Name: chromosome 19 open reading frame 53provided by HGNC
Primary source: HGNC:24991
Locus tag: HSPC023
See related: Ensembl:ENSG00000104979; HPRD:13687
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: LYDG10; HSPC023

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Genomic context

Location :: 19p13.2

Sequence :: Chromosome: 19; NC_000019.9 (13885257..13889587)

See C19orf53 in Epigenomics, MapViewer

Chromosome 19 - NC_000019.9 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description
BioGRID:118798	BioGRID:113164	UBC		BioGRID	PubMed	Affinity Capture-MS

General gene information

Markers

D19S1134 (e-PCR)
- UniSTS:22791

A007D32 (e-PCR)
- UniSTS:17044

RH91188 (e-PCR)
- UniSTS:89060

HSPC023_9568 (e-PCR)
- UniSTS:468467

Homology

Homologs of the C19orf53 gene: The C19orf53 gene is conserved in chimpanzee, , dog, cow, mouse, rat, and zebrafish.
Map Viewer (Mouse, Rat)

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General protein information

Preferred Names: leydig cell tumor 10 kDa protein homolog

Names: leydig cell tumor 10 kDa protein homolog

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_014047.2 → NP_054766.1 leydig cell tumor 10 kDa protein homolog

Status: VALIDATED

Source sequence(s)

AC008686, AI689503, BC015465, DA768829

Consensus CDS

CCDS12298.1

UniProtKB/Swiss-Prot

Q9UNZ5

Related

ENSP00000221576, ENST00000221576

Conserved Domains (1) summary

pfam09495
Location:30 – 67
Blast Score: 83

DUF2462; Protein of unknown function (DUF2462)

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000019.9 Reference GRCh37.p5 Primary Assembly

Range

13885257..13889587

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000151.1 Alternate HuRef

Range

13456894..13461220

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC008686.8 (136502..140760)	None
genomic	CH471106.1	EAW84372.1
mRNA	AF078852.1	AAD44484.1
mRNA	AF086483.1	None
mRNA	AI689503.1	None
mRNA	AK311855.1	BAG34796.1
mRNA	BC015465.2	AAH15465.1
mRNA	DA768829.1	None
other-genetic	DQ891569.2	ABM82495.1
other-genetic	DQ894761.2	ABM85687.1