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Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D [ Rattus norvegicus (Norway rat) ]

Gene ID: 287585, updated on 26-May-2016
Official Symbol
Ppm1dprovided by RGD
Official Full Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Dprovided by RGD
Primary source
RGD:1305460
See related
Ensembl:ENSRNOG00000003329
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Wip1
Orthologs
Location:
10q26
Exon count:
6
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (72909550..72945884)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (72813803..72849854)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1) Neighboring gene amyloid beta precursor protein binding protein 2 Neighboring gene breast carcinoma amplified sequence 3 Neighboring gene uncharacterized LOC102554092 Neighboring gene T-box 2

  • p53 pathway, organism-specific biosystem (from WikiPathways)
    p53 pathway, organism-specific biosystemp53 (also known as protein 53 or tumor protein 53), is a transcription factor which in humans is encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cyc...
  • p53 signaling pathway, organism-specific biosystem (from KEGG)
    p53 signaling pathway, organism-specific biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...
  • p53 signaling pathway, conserved biosystem (from KEGG)
    p53 signaling pathway, conserved biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
mitogen-activated protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
G2/M transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
cellular response to starvation IEP
Inferred from Expression Pattern
more info
PubMed 
peptidyl-threonine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
peptidyl-threonine dephosphorylation ISO
Inferred from Sequence Orthology
more info
 
response to bacterium IEA
Inferred from Electronic Annotation
more info
 
response to bacterium ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
Preferred Names
protein phosphatase 1D
Names
p53-induced protein phosphatase 1
protein phosphatase 1D magnesium-dependent, delta isoform
NP_001099295.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105825.2NP_001099295.2  protein phosphatase 1D

    See identical proteins and their annotated locations for NP_001099295.2

    Status: VALIDATED

    Source sequence(s)
    AABR07030169, BC162058, FM140338
    UniProtKB/TrEMBL
    B1WCA0
    Related
    ENSRNOP00000004540, ENSRNOT00000004540
    Conserved Domains (1) summary
    cd00143
    Location:84368
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    72909550..72945884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    69098036..69134596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)