Nmral1 NmrA like redox sensor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Nmral1provided by RGD
Full Name: NmrA like redox sensor 1provided by RGD
Primary source: RGD:1311451
See related: Ensembl:ENSRNOG00000003794 AllianceGenome:RGD:1311451
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1311451
Summary: Predicted to enable identical protein binding activity. Predicted to be located in nucleoplasm. Orthologous to human NMRAL1 (NmrA like redox sensor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 81.4), Liver (RPKM 58.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (11348080..11356621)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (10841693..10850199)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (11045924..11055154)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nmrA-like family domain-containing protein 1

Names: NmrA-like family domain containing 1; nmrA-like family domain-containing protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191588.1 → NP_001178517.1 nmrA-like family domain-containing protein 1

See identical proteins and their annotated locations for NP_001178517.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

A0A8I6G633, A6K4R5, D3ZDB9

Related

ENSRNOP00000081541.1, ENSRNOT00000114833.1

Conserved Domains (2) summary

cd05251
Location:7 → 255

NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs

COG0702
Location:5 → 212

YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

11348080..11356621

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006245784.3 → XP_006245846.1 nmrA-like family domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A0G2K5K3, D3ZDB9

Related

ENSRNOP00000073458.1

Conserved Domains (2) summary

cd05251
Location:7 → 249

NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs

COG0702
Location:5 → 206

YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]
XM_039085336.2 → XP_038941264.1 nmrA-like family domain-containing protein 1 isoform X4

Conserved Domains (1) summary

cd05251
Location:7 → 172

NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs
XM_063268526.1 → XP_063124596.1 nmrA-like family domain-containing protein 1 isoform X3
XM_039085335.2 → XP_038941263.1 nmrA-like family domain-containing protein 1 isoform X2

UniProtKB/TrEMBL

D3ZDB9

Related

ENSRNOP00000005109.6

Conserved Domains (1) summary

cl21454
Location:1 → 176

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins