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KRT6C keratin 6C [ Homo sapiens (human) ]

Gene ID: 286887, updated on 17-Apr-2014
Official Symbol
KRT6Cprovided by HGNC
Official Full Name
keratin 6Cprovided by HGNC
Primary source
HGNC:20406
See related
Ensembl:ENSG00000170465; HPRD:17247; MIM:612315; Vega:OTTHUMG00000169596
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
K6E; KRT6E; PPKNEFD
Summary
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Location :
12q13.13
Sequence :
Chromosome: 12; NC_000012.12 (52468516..52473785, complement)
See KRT6C in Epigenomics, MapViewer

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene keratin 75 Neighboring gene keratin 6B Neighboring gene keratin 6A Neighboring gene keratin 5

Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
intermediate filament NAS
Non-traceable Author Statement
more info
PubMed 
keratin filament IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
keratin, type II cytoskeletal 6C
Names
keratin, type II cytoskeletal 6C
K6C
CK-6C
CK-6E
keratin 6E
keratin-6C
keratin K6h
cytokeratin-6C
cytokeratin-6E
type-II keratin Kb12

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012416.1 RefSeqGene

    Range
    5001..10270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_173086.4NP_775109.2  keratin, type II cytoskeletal 6C

    See proteins identical to NP_775109.2

    Status: REVIEWED

    Source sequence(s)
    AC055736, BC110639
    Consensus CDS
    CCDS8829.1
    UniProtKB/Swiss-Prot
    P48668
    Related
    ENSP00000252250, OTTHUMP00000241633, ENST00000252250, OTTHUMT00000404976
    Conserved Domains (2) summary
    pfam00038
    Location:162475
    Blast Score: 1074
    Filament; Intermediate filament protein
    cl19113
    Location:370481
    Blast Score: 92
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38 Primary Assembly

    Range
    52468516..52473785, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000144.1 Alternate HuRef

    Range
    49906198..49911468, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    52829152..52834426, complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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