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    ZNF789 zinc finger protein 789 [ Homo sapiens ]

    Gene ID: 285989, updated on 11-May-2012
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    Summary

    Official Symbol
    ZNF789provided by HGNC
    Official Full Name
    zinc finger protein 789provided by HGNC
    Primary source
    HGNC:27801
    See related
    Ensembl:ENSG00000198556; HPRD:14161; Vega:OTTHUMG00000154601
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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    Genomic context

    Location :
    7q22.1
    Sequence :
    Chromosome: 7; NC_000007.13 (99070515..99085217)
    See ZNF789 in Epigenomics, MapViewer

    Chromosome 7 - NC_000007.13Genomic Context describing neighboring genes Neighboring gene ATP5J2-PTCD1 readthrough Neighboring gene SAP domain containing ribonucleoprotein pseudogene Neighboring gene cleavage and polyadenylation specific factor 4, 30kDa Neighboring gene ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 Neighboring gene zinc finger protein 394 Neighboring gene zinc finger with KRAB and SCAN domains 5

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. Vanderwerf SM, et al. Blood, 2009 Dec 17. PMID 19850743.
    2. Transcriptome analysis of human gastric cancer. Oh JH, et al. Mamm Genome, 2005 Dec. PMID 16341674.
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
    4. Human chromosome 7: DNA sequence and biology. Scherer SW, et al. Science, 2003 May 2. PMID 12690205.
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:130267 BioGRID:113164 UBC    BioGRID  PubMed Reconstituted Complex 
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    General gene information

    Markers

    Genotypes

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    intracellular IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    zinc finger protein 789
    Names
    zinc finger protein 789
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013258.1 → NP_001013276.1  zinc finger protein 789 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two 3' exons, but has an alternate 3' exon, as compared to variant 1. The encoded isoform 2 has a shorter and distinct C-terminus, as compared to isoform 1.
      Source sequence(s)
      AK093141, BC031249, BM840763
      Consensus CDS
      CCDS34694.1
      UniProtKB/TrEMBL
      A6NH61
      Related
      ENSP00000369047, OTTHUMP00000214545, ENST00000379724, OTTHUMT00000354146
      Conserved Domains (1) summary
      cd07765
      Location:11 – 50
      Blast Score: 181
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box.

    2. NM_213603.2 → NP_998768.2  zinc finger protein 789 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK093141, BC089424, BI767175
      Consensus CDS
      CCDS34693.1
      UniProtKB/Swiss-Prot
      Q5FWF6
      Related
      ENSP00000331927, OTTHUMP00000206245, ENST00000331410, OTTHUMT00000336266
      Conserved Domains (4) summary
      COG5048
      Location:253 – 313
      Blast Score: 93
      COG5048; FOG: Zn-finger [General function prediction only]
      cd07765
      Location:11 – 50
      Blast Score: 197
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box.
      smart00349
      Location:11 – 71
      Blast Score: 271
      KRAB; krueppel associated box
      pfam13465
      Location:271 – 296
      Blast Score: 88
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000007.13 Reference GRCh37.p5 Primary Assembly

      Range
      99070515..99085217
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000139.1 Alternate HuRef

      Range
      93707138..93721739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CRA_TCAGchr7v2

    Genomic

    1. AC_000068.1 Alternate CRA_TCAGchr7v2

      Range
      98430287..98444989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC073063.12 (30884..45586) None
    genomic CH236956.1 EAL23875.1
      EAL23876.1
    genomic CH236956.1 EAL23875.1
      EAL23876.1
    genomic CH471091.2 EAW76660.1
    mRNA AK093141.1 None
    mRNA AK131429.1 BAD18576.1
    mRNA AK309467.1 None
    mRNA BC031249.1 None
    mRNA BC050286.1 None
    mRNA BC089424.1 AAH89424.2
    mRNA BI767175.1 None
    mRNA BM840763.1 None
    mRNA BX648360.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FWF6.3 GenPept UniProtKB/Swiss-Prot:Q5FWF6
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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