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FAM98B family with sequence similarity 98 member B [ Homo sapiens (human) ]

Gene ID: 283742, updated on 8-May-2016
Official Symbol
FAM98Bprovided by HGNC
Official Full Name
family with sequence similarity 98 member Bprovided by HGNC
Primary source
HGNC:HGNC:26773
See related
Ensembl:ENSG00000171262 HPRD:08786; MIM:616142; Vega:OTTHUMG00000129831
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
15q14
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 15 NC_000015.10 (38454127..38487710)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (38746328..38777063)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928227 Neighboring gene sprouty related EVH1 domain containing 1 Neighboring gene CTD small phosphatase 2 pseudogene Neighboring gene uncharacterized LOC105370774 Neighboring gene RAS guanyl releasing protein 1 Neighboring gene uncharacterized LOC105370775

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study of atypical psychosis.
NHGRI GWA Catalog
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Rev rev HIV-1 Rev interacting protein, family with sequence similarity 98, member B (FAM98B), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with FAM98B is increased by RRE PubMed

Go to the HIV-1, Human Interaction Database

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • tRNA processing, organism-specific biosystem (from REACTOME)
    tRNA processing, organism-specific biosystemGenes encoding transfer RNAs (tRNAs) are transcribed by RNA polymerase III in the nucleus and by mitochondrial RNA polymerase in the mitochondrion.In the nucleus transcription reactions produce precu...
  • tRNA processing in the nucleus, organism-specific biosystem (from REACTOME)
    tRNA processing in the nucleus, organism-specific biosystemGenes encoding transfer RNAs are transcribed in the nucleus by RNA polymerase III. (Distinct processes of transcription and processing also occur in mitochondria.) The initial transcripts, pre-tRNAs,...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ38426

Gene Ontology Provided by GOA

Function Evidence Code Pubs
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
tRNA splicing, via endonucleolytic cleavage and ligation TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
tRNA-splicing ligase complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
protein FAM98B
Names
family with sequence similarity 98, member B

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173611.3NP_775882.2  protein FAM98B

    Status: VALIDATED

    Source sequence(s)
    AI638256, BC035600, BC045690, BP872319, BU633364, BX454964, DA118586, DA520319, DB552059
    Consensus CDS
    CCDS10047.2
    UniProtKB/Swiss-Prot
    Q52LJ0
    Related
    ENSP00000380734, OTTHUMP00000160268, ENST00000397609, OTTHUMT00000252070
    Conserved Domains (1) summary
    pfam10239
    Location:16330
    DUF2465; Protein of unknown function (DUF2465)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p2 Primary Assembly

    Range
    38454127..38487710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 Alternate CHM1_1.1

    Range
    38865511..38899038
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001042429.1: Suppressed sequence

    Description
    NM_001042429.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.