Display Settings:

Format

Send to:

Choose Destination

    SLC22A24 solute carrier family 22, member 24 [ Homo sapiens ]

    Gene ID: 283238, updated on 11-May-2012

    Summary

    Official Symbol
    SLC22A24provided by HGNC
    Official Full Name
    solute carrier family 22, member 24provided by HGNC
    Primary source
    HGNC:28542
    See related
    Ensembl:ENSG00000197658; HPRD:14591; MIM:611698; Vega:OTTHUMG00000165372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NET46; MGC34821
    Summary
    SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]

    Genomic context

    Location :
    11q12.3
    Sequence :
    Chromosome: 11; NC_000011.9 (62847412..62911693, complement)
    See SLC22A24 in Epigenomics, MapViewer

    Chromosome 11 - NC_000011.9Genomic Context describing neighboring genes Neighboring gene pituitary tumor-transforming 1 pseudogene Neighboring gene tubulin, alpha 4a pseudogene Neighboring gene ribosomal protein L29 pseudogene 22 Neighboring gene solute carrier family 22, member 25 Neighboring gene cyclin D2 pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:129508 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    solute carrier family 22 member 24
    Names
    solute carrier family 22 member 24

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136506.2NP_001129978.2  solute carrier family 22 member 24

      Status: VALIDATED

      Source sequence(s)
      AP001858
      Related
      ENSP00000396586, OTTHUMP00000229553, ENST00000417740, OTTHUMT00000383747
      Conserved Domains (2) summary
      cd06174
      Location:125280
      Blast Score: 176
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:11526
      Blast Score: 909
      2A0119; cation transport protein

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000011.9 Reference GRCh37.p5 Primary Assembly

      Range
      62847412..62911693, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000143.1 Alternate HuRef

      Range
      59176431..59240645, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_173586.1: Suppressed sequence

      Description
      NM_173586.1: This RefSeq was temporarily suppressed because there is not sufficient data to support this transcript.

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AP001858.4 (105717..169998) None
    mRNA BC034394.1 AAH34394.1
    other-genetic DQ890828.2 ABM81754.1
    other-genetic DQ893983.2 ABM84909.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N4F4.1 GenPept UniProtKB/Swiss-Prot:Q8N4F4

      Supplemental Content

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...