TAP2 transporter 2, ATP binding cassette subfamily B member [Bos taurus (cattle)] - Gene

Summary

Gene symbol: TAP2
Gene description: transporter 2, ATP binding cassette subfamily B member
See related: BGD:BT10502; Ensembl:ENSBTAG00000003038
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ABCB3
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (7138820..7146579, complement)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ABC-type oligopeptide transporter activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed
enables MHC protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptide transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of TAP complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: antigen peptide transporter 2

Names: ABC-transporter; ATP-binding cassette, sub-family B (MDR/TAP), member 3; transporter 2, ABC(ATP binding cassette)

NP_776647.1

EC 7.4.2.14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174222.2 → NP_776647.1 antigen peptide transporter 2

See identical proteins and their annotated locations for NP_776647.1

Status: PROVISIONAL

Source sequence(s)

AF318024

UniProtKB/TrEMBL

F1MCG5, F1MCG6, Q8SQ31

Related

ENSBTAP00000003953.6, ENSBTAT00000003953.7

Conserved Domains (3) summary

COG1132
Location:134 → 697

MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]

pfam00664
Location:160 → 415

ABC_membrane; ABC transporter transmembrane region

cl21455
Location:456 → 679

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases