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TGM2 transglutaminase 2 [ Bos taurus (cattle) ]

Gene ID: 281528, updated on 26-Jul-2015
Gene symbol
TGM2
Gene description
transglutaminase 2
See related
BGD:BT15293; Ensembl:ENSBTAG00000016208
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
See TGM2 in MapViewer
Location:
chromosome: 13
Exon count:
13
Annotation release Status Assembly Chr Location
104 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 13 AC_000170.1 (67663135..67697607, complement)

Chromosome 13 - AC_000170.1Genomic Context describing neighboring genes Neighboring gene TELO2 interacting protein 1 Neighboring gene regulation of nuclear pre-mRNA domain containing 1B Neighboring gene KIAA1755 ortholog Neighboring gene uncharacterized LOC104973875 Neighboring gene bactericidal/permeability-increasing protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Huntington's disease, organism-specific biosystem (from KEGG)
    Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • Huntington's disease, conserved biosystem (from KEGG)
    Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein-glutamine gamma-glutamyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
apoptotic cell clearance IEA
Inferred from Electronic Annotation
more info
 
branching involved in salivary gland morphogenesis IEA
Inferred from Electronic Annotation
more info
 
negative regulation of endoplasmic reticulum calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 
peptide cross-linking IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitochondrial calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 
salivary gland cavitation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
focal adhesion IEA
Inferred from Electronic Annotation
more info
 
intrinsic component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
protein-glutamine gamma-glutamyltransferase 2
Names
TG(C)
TGC
TGase C
TGase-2
tissue transglutaminase
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
transglutaminase C
transglutaminase-2
NP_803473.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177507.2NP_803473.1  protein-glutamine gamma-glutamyltransferase 2

    See identical proteins and their annotated locations for NP_803473.1

    Status: PROVISIONAL

    Source sequence(s)
    X60686
    UniProtKB/Swiss-Prot
    P51176
    Related
    ENSBTAP00000021569, ENSBTAT00000021569
    Conserved Domains (4) summary
    smart00460
    Location:269361
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:271369
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00868
    Location:5124
    Transglut_N; Transglutaminase family
    pfam00927
    Location:587686
    Transglut_C; Transglutaminase family, C-terminal ig like domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1.1 Primary Assembly

Genomic

  1. AC_000170.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    67663135..67697607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_4.6.1

Genomic

  1. NC_007311.5 Alternate Btau_4.6.1

    Range
    67578510..67612990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)