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RGS9 regulator of G protein signaling 9 [ Bos taurus (cattle) ]

Gene ID: 281453, updated on 3-Apr-2024

Summary

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Official Symbol
RGS9provided by VGNC
Official Full Name
regulator of G protein signaling 9provided by VGNC
Primary source
VGNC:VGNC:33926
See related
Ensembl:ENSBTAG00000017751
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (61983611..62043250)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene archaelysin family metallopeptidase 2 Neighboring gene G protein subunit alpha 13 Neighboring gene uncharacterized LOC101907107 Neighboring gene uncharacterized LOC112442742 Neighboring gene uncharacterized LOC112442583 Neighboring gene axin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment. Bernier SC, et al. Biochim Biophys Acta Biomembr, 2021 Apr 1. PMID 33453187
  2. The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunit. Makino ER, et al. Proc Natl Acad Sci U S A, 1999 Mar 2. PMID 10051575, Free PMC Article
  3. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Slep KC, et al. Nature, 2001 Feb 22. PMID 11234020
  4. RGS9, a GTPase accelerator for phototransduction. He W, et al. Neuron, 1998 Jan. PMID 9459445
  5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment.
    Title: Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC159844

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
regulator of G-protein signaling 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174170.2 → NP_776595.1  regulator of G-protein signaling 9

    See identical proteins and their annotated locations for NP_776595.1

    Status: PROVISIONAL

    Source sequence(s)
    AF011357
    UniProtKB/Swiss-Prot
    O46469
    UniProtKB/TrEMBL
    F1MYX4
    Conserved Domains (4) summary
    smart00224
    Location:222 → 280
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:292 → 412
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:22 → 109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:106 → 205
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61983611..62043250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024979596.2 → XP_024835364.1  regulator of G-protein signaling 9 isoform X4

    Related
    ENSBTAP00000099733.1, ENSBTAT00000095863.1
    Conserved Domains (3) summary
    smart00224
    Location:196 → 254
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:266 → 386
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:1 → 83
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  2. XM_024979594.2 → XP_024835362.1  regulator of G-protein signaling 9 isoform X2

    Conserved Domains (3) summary
    smart00224
    Location:222 → 280
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:292 → 412
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:22 → 109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  3. XM_059877711.1 → XP_059733694.1  regulator of G-protein signaling 9 isoform X5

  4. XM_024979595.2 → XP_024835363.1  regulator of G-protein signaling 9 isoform X3

    Conserved Domains (3) summary
    smart00224
    Location:222 → 280
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:292 → 412
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:22 → 109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  5. XM_024979593.2 → XP_024835361.1  regulator of G-protein signaling 9 isoform X1

    Related
    ENSBTAP00000023605.7, ENSBTAT00000023605.7
    Conserved Domains (3) summary
    smart00224
    Location:222 → 280
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:292 → 412
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:22 → 109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  6. XM_024979597.2 → XP_024835365.1  regulator of G-protein signaling 9 isoform X6

    Conserved Domains (3) summary
    smart00224
    Location:169 → 227
    GGL; G protein gamma subunit-like motifs
    cd08739
    Location:239 → 359
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd04450
    Location:22 → 109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  7. XM_059877712.1 → XP_059733695.1  regulator of G-protein signaling 9 isoform X7

RNA

  1. XR_003030579.2 RNA Sequence

  2. XR_003030580.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O46469.1 GenPept UniProtKB/Swiss-Prot:O46469

Gene LinkOut

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