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GHRL ghrelin/obestatin prepropeptide [ Bos taurus (cattle) ]

Gene ID: 281192, updated on 7-Aug-2014
Official Symbol
GHRL
Official Full Name
ghrelin/obestatin prepropeptide
Locus tag
BOS_21138
See related
BGD:BT12441; Ensembl:ENSBTAG00000012328
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
Gh1-1
See GHRL in MapViewer
Location:
chromosome: 22
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Bos_taurus_UMD_3.1 (GCF_000003055.4) 22 AC_000179.1 (54945532..54949999, complement)

Chromosome 22 - AC_000179.1Genomic Context describing neighboring genes Neighboring gene zinc finger, DHHC-type containing 3 Neighboring gene transmembrane protein 42 Neighboring gene SEC13 homolog (S. cerevisiae) Neighboring gene ATPase, Ca++ transporting, plasma membrane 2 Neighboring gene microRNA mir-885

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ghrelin receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
 
growth hormone-releasing hormone activity ISS
Inferred from Sequence or Structural Similarity
more info
 
hormone activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein tyrosine kinase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
actin polymerization or depolymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
activation of MAPK activity ISS
Inferred from Sequence or Structural Similarity
more info
 
decidualization ISS
Inferred from Sequence or Structural Similarity
more info
 
dendrite development ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of endothelial cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of inflammatory response ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of insulin secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of interleukin-1 beta production ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of interleukin-6 biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of tumor necrosis factor biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cytosolic calcium ion concentration ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of insulin secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein tyrosine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of response to food ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of response to food ISS
Inferred from Sequence or Structural Similarity
more info
 
response to estrogen ISS
Inferred from Sequence or Structural Similarity
more info
 
response to hormone ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
axon ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
appetite-regulating hormone
Names
appetite-regulating hormone
motilin-related peptide
growth hormone secretagogue
ghrelin/obestatin preprohormone
growth hormone-releasing peptide

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174067.2NP_776492.1  appetite-regulating hormone precursor

    See proteins identical to NP_776492.1

    Status: PROVISIONAL

    Source sequence(s)
    AF350329
    UniProtKB/TrEMBL
    B9DQV0
    UniProtKB/Swiss-Prot
    Q9BDJ6
    Related
    ENSBTAP00000016350, ENSBTAT00000016350
    Conserved Domains (2) summary
    pfam04643
    Location:55116
    Blast Score: 209
    Motilin_assoc; Motilin/ghrelin-associated peptide
    pfam04644
    Location:2450
    Blast Score: 102
    Motilin_ghrelin; Motilin/ghrelin

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1 Primary Assembly

Genomic

  1. AC_000179.1 

    Range
    54945532..54949999
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005223023.1XP_005223080.1  

    See proteins identical to XP_005223080.1

    UniProtKB/TrEMBL
    A6QLN4
    Related
    ENSBTAP00000041811, ENSBTAT00000044304
    Conserved Domains (2) summary
    pfam04643
    Location:55109
    Blast Score: 204
    Motilin_assoc; Motilin/ghrelin-associated peptide
    pfam04644
    Location:2450
    Blast Score: 97
    Motilin_ghrelin; Motilin/ghrelin
  2. XM_005223021.1XP_005223078.1  

    Conserved Domains (2) summary
    pfam04643
    Location:125179
    Blast Score: 213
    Motilin_assoc; Motilin/ghrelin-associated peptide
    pfam04644
    Location:94120
    Blast Score: 101
    Motilin_ghrelin; Motilin/ghrelin
  3. XM_005223024.1XP_005223081.1  

    See proteins identical to XP_005223081.1

    UniProtKB/TrEMBL
    A6QLN4
    Conserved Domains (2) summary
    pfam04643
    Location:55109
    Blast Score: 204
    Motilin_assoc; Motilin/ghrelin-associated peptide
    pfam04644
    Location:2450
    Blast Score: 97
    Motilin_ghrelin; Motilin/ghrelin
  4. XM_005223022.1XP_005223079.1  

    See proteins identical to XP_005223079.1

    UniProtKB/TrEMBL
    A6QLN4
    Conserved Domains (2) summary
    pfam04643
    Location:55109
    Blast Score: 204
    Motilin_assoc; Motilin/ghrelin-associated peptide
    pfam04644
    Location:2450
    Blast Score: 97
    Motilin_ghrelin; Motilin/ghrelin

Alternate Btau_4.6.1

Genomic

  1. NC_007320.5 

    Range
    55447445..55451455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)