SRY sex determining region Y [Bos taurus (cattle)] - Gene

Summary

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Gene symbol: SRY
Gene description: sex determining region Y
Locus tag: BOS_12769
See related: Ensembl:ENSBTAG00000047779
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos

Genomic context

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Location :: chromosome: Y

Sequence :: Chromosome: 13; AC_000170.1 (5424637..5425326, complement)

See SRY in MapViewer

Chromosome 13 - AC_000170.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of mtDNA control region sequences and SRY gene sequences indicated more contribution to the Yunnan cattle from B. indicus than from B. taurus
Title: Genetic diversity and origin of Gayal and cattle in Yunnan revealed by mtDNA control region and SRY gene sequence variation.
New insights into SRY regulation through identification of 5' conserved sequence are reported.
Title: New insights into SRY regulation through identification of 5' conserved sequences.
Mapped to the bovine Y chromosome (BTAY) by fluorescence in situ hybridization (FISH) and/or radiation hybrid (RH) mapping.
Title: Assignment of SRY, ANT3, and CSF2RA to the bovine Y chromosome by FISH and RH mapping.

Submit: New GeneRIF Correction

Pathways from BioSystems

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Androgen Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
Androgen Receptor Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...

General gene information

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Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
RNA polymerase II core promoter sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	IEA Inferred from Electronic Annotation more info
RNA polymerase II transcription corepressor activity	IEA Inferred from Electronic Annotation more info
calmodulin binding	IEA Inferred from Electronic Annotation more info
transcription factor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
Sertoli cell development	IEA Inferred from Electronic Annotation more info
face development	IEA Inferred from Electronic Annotation more info
hypothalamus development	IEA Inferred from Electronic Annotation more info
male sex determination	IEA Inferred from Electronic Annotation more info
organ morphogenesis	IEA Inferred from Electronic Annotation more info
pituitary gland development	IEA Inferred from Electronic Annotation more info
positive regulation of male gonad development	IEA Inferred from Electronic Annotation more info
sensory organ development	IEA Inferred from Electronic Annotation more info
spermatid differentiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info
nuclear speck	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sex-determining region Y protein

Names: sex-determining region Y protein; sex determining factor Y; testis-determining factor; sex-determining region of the Y-chromosome

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014385.1 → NP_001014407.1 sex-determining region Y protein

Status: PROVISIONAL

Source sequence(s)

AB039748

UniProtKB/TrEMBL

B6S2A2

UniProtKB/Swiss-Prot

Q03255

Related

ENSBTAP00000056194, ENSBTAT00000062957

Conserved Domains (1) summary

cd01388
Location:53 – 114
Blast Score: 221

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

RefSeqs of Annotated Genomes: Build 6.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1 Primary Assembly

Genomic

AC_000170.1 Reference Bos_taurus_UMD_3.1 Primary Assembly

Range

5424637..5425326, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_4.6.1

Genomic

NC_016145.1 Alternate Btau_4.6.1

Range

42225210..42225899, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AB039748.1	BAA92368.1
genomic	AC232880.1 (11306..11995)	None
genomic	AF148462.1	AAD31531.1
genomic	AY189027.1	AAO25620.1
genomic	D10843.1	BAA86975.1
genomic	DAAA02035098.1 (83380..84069)	None
genomic	DQ336526.2	ABC67486.1
genomic	EU233320.1	ABW89571.1
genomic	EU294189.1	ABY19364.1
genomic	EU581861.1	ACE73647.1
genomic	GJ062257.1	DAA23663.1	Hereford
genomic	U15569.1	AAA50602.1
genomic	Z30327.1	CAA82981.1