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BIN1 bridging integrator 1 [ Homo sapiens (human) ]

Gene ID: 274, updated on 26-Aug-2014
Official Symbol
BIN1provided by HGNC
Official Full Name
bridging integrator 1provided by HGNC
Primary source
HGNC:1052
See related
Ensembl:ENSG00000136717; HPRD:03150; MIM:601248; Vega:OTTHUMG00000131465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AMPH2; AMPHL; SH3P9
Summary
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
See BIN1 in Epigenomics, MapViewer
Location:
2q14
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 2 NC_000002.12 (127048023..127107327, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (127805599..127864903, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 2 Neighboring gene glycophorin C (Gerbich blood group) Neighboring gene cytochrome P450, family 27, subfamily C, polypeptide 1 Neighboring gene WW domain binding protein 11 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Autosomal recessive centronuclear myopathy
MedGen: C0410204 OMIM: 255200 GeneReviews: Not available
Compare labs

NHGRI GWAS Catalog

Description
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
NHGRI GWA Catalog
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
NHGRI GWA Catalog
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
NHGRI GWA Catalog
Genome-wide association study of Alzheimer's disease.
NHGRI GWA Catalog
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
NHGRI GWA Catalog
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
NHGRI GWA Catalog
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC10367, DKFZp547F068

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTPase binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
tau protein binding IPI
Inferred from Physical Interaction
more info
 
Process Evidence Code Pubs
cell proliferation TAS
Traceable Author Statement
more info
PubMed 
endocytosis IEA
Inferred from Electronic Annotation
more info
 
lipid tube assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of astrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 
regulation of cell cycle arrest IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
I band ISS
Inferred from Sequence or Structural Similarity
more info
 
T-tubule ISS
Inferred from Sequence or Structural Similarity
more info
 
Z disc ISS
Inferred from Sequence or Structural Similarity
more info
 
actin cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
 
axon initial segment ISS
Inferred from Sequence or Structural Similarity
more info
 
axon terminus IEA
Inferred from Electronic Annotation
more info
 
cerebellar mossy fiber IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
 
lipid tube IMP
Inferred from Mutant Phenotype
more info
PubMed 
node of Ranvier ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 
varicosity IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
myc box-dependent-interacting protein 1
Names
myc box-dependent-interacting protein 1
amphiphysin II
amphiphysin-like protein
box dependant MYC interacting protein 1
box-dependent myc-interacting protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012042.1 

    Range
    4962..64266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_004305.3NP_004296.1  myc box-dependent-interacting protein 1 isoform 8

    See proteins identical to NP_004296.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks five in-frame exons and has an additional in-frame exon in the coding region, compared to variant 1. Isoform 8 is shorter than isoform 1. It is expressed in muscle and localizes to the nucleus.
    Source sequence(s)
    AF070576, BM711160, CF594020, U68485
    Consensus CDS
    CCDS2137.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000315284, OTTHUMP00000162185, ENST00000352848, OTTHUMT00000254306
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1062
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:382453
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  2. NM_139343.2NP_647593.1  myc box-dependent-interacting protein 1 isoform 1

    See proteins identical to NP_647593.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform, which is cytoplasmic. Isoform 1, also called IIa and S11R3-a, binds dynamin, synaptojanin, and clathrin. This isoform is expressed exclusively in the brain and is concentrated in nerve terminals.
    Source sequence(s)
    AF004015, AF070576, BM711160, CF594020, U87558
    Consensus CDS
    CCDS2138.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000316779, OTTHUMP00000162177, ENST00000316724, OTTHUMT00000254298
    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1051
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:521592
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  3. NM_139344.2NP_647594.1  myc box-dependent-interacting protein 1 isoform 2

    See proteins identical to NP_647594.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. Isoform 2, also called IId and S1/R3-6, is shorter than isoform 1 and binds dynamin, synaptojanin, and clathrin.
    Source sequence(s)
    AC012508, AF043901, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS2139.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000350654, OTTHUMP00000162178, ENST00000357970, OTTHUMT00000254299
    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1054
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:478549
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  4. NM_139345.2NP_647595.1  myc box-dependent-interacting protein 1 isoform 3

    See proteins identical to NP_647595.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks three in-frame exons in the coding region, compared to variant 1. Isoform 3, also called IIc1, is shorter than isoform 1 and binds dynamin and synaptojanin.
    Source sequence(s)
    AC012508, AF043899, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS2140.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000315388, OTTHUMP00000162184, ENST00000351659, OTTHUMT00000254305
    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1042
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:434505
    Blast Score: 392
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  5. NM_139346.2NP_647596.1  myc box-dependent-interacting protein 1 isoform 4

    See proteins identical to NP_647596.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks four in-frame exons and has an additional in-frame exon in the coding region, compared to variant 1. Isoform 4 is shorter than isoform 1.
    Source sequence(s)
    AF068918, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS2141.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000259238, OTTHUMP00000162181, ENST00000259238, OTTHUMT00000254302
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1061
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:425496
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  6. NM_139347.2NP_647597.1  myc box-dependent-interacting protein 1 isoform 5

    See proteins identical to NP_647597.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks three in-frame exons in the coding region, compared to variant 1. Isoform 5, also called IIb, is shorter than isoform 1 and binds dynamin, synaptojanin, and endophilin.
    Source sequence(s)
    AC012508, AF043898, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS2142.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000315411, OTTHUMP00000162182, ENST00000346226, OTTHUMT00000254303
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1080
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:446517
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  7. NM_139348.2NP_647598.1  myc box-dependent-interacting protein 1 isoform 6

    See proteins identical to NP_647598.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks four in-frame exons in the coding region, compared to variant 1. Isoform 6, also called subtype 2, is shorter than isoform 1.
    Source sequence(s)
    AF068917, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS42744.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000376760, OTTHUMP00000162179, ENST00000393040, OTTHUMT00000254300
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1067
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:410481
    Blast Score: 389
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  8. NM_139349.2NP_647599.1  myc box-dependent-interacting protein 1 isoform 7

    See proteins identical to NP_647599.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks three in-frame exons in the coding region, compared to variant 1. Isoform 7, also called IIc2 and S1/R3-c, is shorter than isoform 1 and binds dynamin and synaptojanin.
    Source sequence(s)
    AC012508, AF043900, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS42743.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000376761, OTTHUMP00000162183, ENST00000393041, OTTHUMT00000254304
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1083
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:403474
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  9. NM_139350.2NP_647600.1  myc box-dependent-interacting protein 1 isoform 9

    See proteins identical to NP_647600.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) lacks five in-frame exons in the coding region, compared to variant 1. Isoform 9, also called BIN1-10, is shorter than isoform 1 and is ubiquitously expressed.
    Source sequence(s)
    AF068914, AF070576, BC004101, BM711160, CF594020
    Consensus CDS
    CCDS46403.1
    UniProtKB/Swiss-Prot
    O00499
    UniProtKB/TrEMBL
    Q9BTH3
    Related
    ENSP00000386797, OTTHUMP00000203785, ENST00000409400, OTTHUMT00000330943
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1068
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:367438
    Blast Score: 389
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  10. NM_139351.2NP_647601.1  myc box-dependent-interacting protein 1 isoform 10

    See proteins identical to NP_647601.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) lacks six in-frame exons in the coding region, compared to variant 1. Isoform 10, also called BIN1-10-13, is shorter than isoform 1 and is ubiquitously expressed.
    Source sequence(s)
    AF068915, AF070576, BM711160, CF594020
    Consensus CDS
    CCDS2143.1
    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000259237, OTTHUMP00000162180, ENST00000348750, OTTHUMT00000254301
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1063
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:337408
    Blast Score: 388
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000002.12 

    Range
    127048023..127107327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263644.1XP_005263701.1  

    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1093
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:490561
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  2. XM_005263647.1XP_005263704.1  

    See proteins identical to XP_005263704.1

    UniProtKB/Swiss-Prot
    O00499
    Related
    ENSP00000365281, OTTHUMP00000203786, ENST00000376113, OTTHUMT00000330944
    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1056
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:352423
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  3. XM_005263643.1XP_005263700.1  

    Conserved Domains (2) summary
    cd07611
    Location:31241
    Blast Score: 1086
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:505576
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  4. XM_006712434.1XP_006712497.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1024
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:368439
    Blast Score: 389
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  5. XM_005263646.1XP_005263703.1  

    See proteins identical to XP_005263703.1

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1028
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:398469
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  6. XM_006712430.1XP_006712493.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1026
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:441512
    Blast Score: 392
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  7. XM_006712433.1XP_006712496.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1017
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:383454
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  8. XM_006712432.1XP_006712495.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1022
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:413484
    Blast Score: 393
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  9. XM_006712429.1XP_006712492.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1036
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:449520
    Blast Score: 395
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  10. XM_006712431.1XP_006712494.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1016
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:426497
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  11. XM_006712428.1XP_006712491.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1020
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:456527
    Blast Score: 393
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  12. XM_006712426.1XP_006712489.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1033
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:492563
    Blast Score: 395
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  13. XM_006712425.1XP_006712488.1  

    Conserved Domains (3) summary
    pfam00859
    Location:298451
    Blast Score: 92
    CTF_NFI; CTF/NF-I family transcription modulation region
    cd07611
    Location:31272
    Blast Score: 1033
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:492563
    Blast Score: 393
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  14. XM_005263642.1XP_005263699.1  

    Conserved Domains (2) summary
    cd07611
    Location:31272
    Blast Score: 1045
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:536607
    Blast Score: 392
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  15. XM_006712424.1XP_006712487.1  

    Conserved Domains (2) summary
    cd07611
    Location:7248
    Blast Score: 1047
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:512583
    Blast Score: 393
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  16. XM_005263648.1XP_005263705.1  

    See proteins identical to XP_005263705.1

    UniProtKB/TrEMBL
    B7Z6Y2
    Conserved Domains (2) summary
    cd07611
    Location:7217
    Blast Score: 1064
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:313384
    Blast Score: 387
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  17. XM_006712427.1XP_006712490.1  

    Conserved Domains (2) summary
    cd07611
    Location:7217
    Blast Score: 1094
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:466537
    Blast Score: 391
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
  18. XM_005263645.1XP_005263702.1  

    Conserved Domains (2) summary
    cd07611
    Location:7217
    Blast Score: 1088
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:481552
    Blast Score: 390
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

Alternate HuRef

Genomic

  1. AC_000134.1 

    Range
    120113344..120172651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 

    Range
    127809107..127868406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)