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ARFIP1 ADP ribosylation factor interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 27236, updated on 8-May-2016
Official Symbol
ARFIP1provided by HGNC
Official Full Name
ADP ribosylation factor interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:21496
See related
Ensembl:ENSG00000164144 HPRD:09331; MIM:605928; Vega:OTTHUMG00000161468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSU52521
Orthologs
Location:
4q31.3
Exon count:
14
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 4 NC_000004.12 (152779937..152911912)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (153701091..153833064)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene transmembrane protein 154 Neighboring gene uncharacterized LOC105377495 Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae) pseudogene Neighboring gene tigger transposable element derived 4 Neighboring gene FH2 domain containing 1 Neighboring gene family with sequence similarity 192, member B pseudogene Neighboring gene uncharacterized LOC729870

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC117369

Gene Ontology Provided by GOA

Function Evidence Code Pubs
phosphatidylinositol-4-phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
intracellular protein transport IDA
Inferred from Direct Assay
more info
PubMed 
regulation of Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of protein secretion IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
trans-Golgi network membrane IDA
Inferred from Direct Assay
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025593.2NP_001020764.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_001020764.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AI634366, AK096509, AK299600, AK304141, BC103759, BC105114
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000348360, OTTHUMP00000220283, ENST00000356064, OTTHUMT00000365035
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  2. NM_001025595.2NP_001020766.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001020766.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 4, and 5 encode the same isoform.
    Source sequence(s)
    AI634366, AK096509, AK299600, AK304141, BC103759, BC105114, DC346238
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000296557, ENST00000353617
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  3. NM_001287431.1NP_001274360.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001274360.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AI634366, AK096509, AK299600, AK304141, BC103759
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000395083, OTTHUMP00000220280, ENST00000451320, OTTHUMT00000365032
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  4. NM_001287432.1NP_001274361.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001274361.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AI634366, AK096509, AK299600, AK304141, AU139844, BC103759, BC105114
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  5. NM_001287433.1NP_001274362.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_001274362.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AI634366, AK096509, AK299600, AK304141, BC103759, BC105114, DA452239
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  6. NM_014447.3NP_055262.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_055262.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AI634366, AK096509, AK290472, AK299600, AK304141
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000384189, OTTHUMP00000220282, ENST00000405727, OTTHUMT00000365034
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p2 Primary Assembly

    Range
    152779937..152911912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531870.1XP_011530172.1  

    See identical proteins and their annotated locations for XP_011530172.1

    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  2. XM_011531869.1XP_011530171.1  

    See identical proteins and their annotated locations for XP_011530171.1

    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  3. XM_011531872.1XP_011530174.1  

    See identical proteins and their annotated locations for XP_011530174.1

    UniProtKB/TrEMBL
    B7ZA10
    Conserved Domains (1) summary
    cd07660
    Location:78278
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  4. XM_011531871.1XP_011530173.1  

    Conserved Domains (1) summary
    cd07660
    Location:129329
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  5. XM_011531868.1XP_011530170.1  

    Conserved Domains (1) summary
    cd07660
    Location:161361
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

RNA

  1. XR_938722.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018915.2 Alternate CHM1_1.1

    Range
    153679057..153811057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)