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HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) [ Homo sapiens (human) ]

Gene ID: 27129, updated on 11-Sep-2014
Official Symbol
HSPB7provided by HGNC
Official Full Name
heat shock 27kDa protein family, member 7 (cardiovascular)provided by HGNC
Primary source
HGNC:HGNC:5249
Locus tag
RP11-5P18.6
See related
Ensembl:ENSG00000173641; HPRD:13684; MIM:610692; Vega:OTTHUMG00000009531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
cvHSP
See HSPB7 in Epigenomics, MapViewer
Location:
1p36.23-p34.3
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 1 NC_000001.11 (16014028..16018790, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (16340523..16346084, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 17 Neighboring gene TBC1 domain family member 3H-like Neighboring gene chromosome 1 open reading frame 64 Neighboring gene chloride channel, voltage-sensitive Ka Neighboring gene family with sequence similarity 131, member C pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ32733, DKFZp779D0968

Gene Ontology Provided by GOA

Function Evidence Code Pubs
filamin binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of heart contraction TAS
Traceable Author Statement
more info
PubMed 
response to unfolded protein TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
Cajal body IEA
Inferred from Electronic Annotation
more info
 
actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
heat shock protein beta-7
Names
heat shock protein beta-7
cardiovascular heat shock protein
heat shock 27kD protein family, member 7 (cardiovascular)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014424.4NP_055239.1  heat shock protein beta-7

    See proteins identical to NP_055239.1

    Status: VALIDATED

    Source sequence(s)
    AJ243191, AK057295, AL355994, BC006319, CR749298
    Consensus CDS
    CCDS30611.1
    UniProtKB/Swiss-Prot
    Q9UBY9
    Related
    ENSP00000310111, OTTHUMP00000011123, ENST00000311890, OTTHUMT00000026334
    Conserved Domains (2) summary
    cd06479
    Location:73153
    ACD_HspB7_like; Alpha crystallin domain (ACD) found in mammalian small heat shock protein (sHsp) HspB7, also known as cardiovascular small heat shock protein (cvHsp), and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect ...
    COG0071
    Location:41167
    IbpA; Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000001.11 

    Range
    16014028..16018790
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000133.1 

    Range
    14859583..14864344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 

    Range
    16139026..16143787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)