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UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [ Homo sapiens (human) ]

Gene ID: 27089, updated on 26-Jun-2015
Official Symbol
UQCRQprovided by HGNC
Official Full Name
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDaprovided by HGNC
Primary source
HGNC:HGNC:29594
See related
HPRD:17941; MIM:612080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
QPC; QCR8; QP-C; UQCR7; MC3DN4
Summary
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
Orthologs
See UQCRQ in Epigenomics, MapViewer
Location:
5q31.1
Exon count:
3
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 5 NC_000005.10 (132866627..132868844)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (132202319..132204536)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene RNA, U7 small nuclear 15 pseudogene Neighboring gene RNA, 5S ribosomal pseudogene 192 Neighboring gene growth differentiation factor 9 Neighboring gene liver expressed antimicrobial peptide 2 Neighboring gene AF4/FMR2 family, member 4 Neighboring gene eukaryotic translation elongation factor 1 alpha 2 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Potential readthrough

Included gene: LEAP2

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ubiquinol-cytochrome-c reductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular metabolic process TAS
Traceable Author Statement
more info
 
cerebellar Purkinje cell layer development IEA
Inferred from Electronic Annotation
more info
 
hippocampus development IEA
Inferred from Electronic Annotation
more info
 
hydrogen ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
hypothalamus development IEA
Inferred from Electronic Annotation
more info
 
midbrain development IEA
Inferred from Electronic Annotation
more info
 
pons development IEA
Inferred from Electronic Annotation
more info
 
pyramidal neuron development IEA
Inferred from Electronic Annotation
more info
 
respiratory electron transport chain TAS
Traceable Author Statement
more info
 
small molecule metabolic process TAS
Traceable Author Statement
more info
 
subthalamus development IEA
Inferred from Electronic Annotation
more info
 
thalamus development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial inner membrane TAS
Traceable Author Statement
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 
respiratory chain IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
cytochrome b-c1 complex subunit 8
Names
cytochrome b-c1 complex subunit 8
complex III subunit 8
complex III subunit VIII
low molecular mass ubiquinone-binding protein (9.5kD)
ubiquinol-cytochrome c reductase complex 9.5 kDa protein
ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
NP_055217.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012221.1 RefSeqGene

    Range
    5001..7218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_014402.4NP_055217.2  cytochrome b-c1 complex subunit 8

    See identical proteins and their annotated locations for NP_055217.2

    Status: REVIEWED

    Source sequence(s)
    AC004500, BU190580, BU953465, CR743513
    Consensus CDS
    CCDS34237.1
    UniProtKB/Swiss-Prot
    O14949
    Conserved Domains (1) summary
    pfam02939
    Location:281
    UcrQ; UcrQ family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p2 Primary Assembly

    Range
    132866627..132868844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018916.2 Alternate CHM1_1.1

    Range
    131635604..131637820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)