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FOXB1 forkhead box B1 [ Homo sapiens (human) ]

Gene ID: 27023, updated on 12-May-2016
Official Symbol
FOXB1provided by HGNC
Official Full Name
forkhead box B1provided by HGNC
Primary source
HGNC:HGNC:3799
See related
Ensembl:ENSG00000171956 HPRD:07017
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FKH5; HFKH-5
Orthologs
Location:
15q22.2
Exon count:
2
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 15 NC_000015.10 (60004222..60005943)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (60296421..60298142)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 18 pseudogene 2 Neighboring gene NMNAT1 pseudogene 5 Neighboring gene uncharacterized LOC105370838 Neighboring gene mesoderm specific transcript pseudogene 2

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
axon target recognition ISS
Inferred from Sequence or Structural Similarity
more info
 
cell migration in diencephalon ISS
Inferred from Sequence or Structural Similarity
more info
 
epithelial cell differentiation involved in mammary gland alveolus development ISS
Inferred from Sequence or Structural Similarity
more info
 
floor plate development ISS
Inferred from Sequence or Structural Similarity
more info
 
hypothalamus cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
inferior colliculus development ISS
Inferred from Sequence or Structural Similarity
more info
 
lactation ISS
Inferred from Sequence or Structural Similarity
more info
 
mammary gland lobule development ISS
Inferred from Sequence or Structural Similarity
more info
 
mammillary body development ISS
Inferred from Sequence or Structural Similarity
more info
 
mammillothalamic axonal tract development ISS
Inferred from Sequence or Structural Similarity
more info
 
midbrain development ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of neuron apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
somitogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
spinal cord development IEA
Inferred from Electronic Annotation
more info
 
telencephalon cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
thalamus development IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
urogenital system development IEA
Inferred from Electronic Annotation
more info
 
visual learning ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
forkhead box protein B1
Names
transcription factor FKH-5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012182.2NP_036314.2  forkhead box protein B1

    See identical proteins and their annotated locations for NP_036314.2

    Status: VALIDATED

    Source sequence(s)
    AC009654, AF071554, DA685771
    Consensus CDS
    CCDS32255.1
    UniProtKB/Swiss-Prot
    Q99853
    Related
    ENSP00000379369, OTTHUMP00000247414, ENST00000396057, OTTHUMT00000416378
    Conserved Domains (1) summary
    cd00059
    Location:1390
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p2 Primary Assembly

    Range
    60004222..60005943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 Alternate CHM1_1.1

    Range
    60414763..60416484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)