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Clip2 CAP-GLY domain containing linker protein 2 [ Mus musculus (house mouse) ]

Gene ID: 269713, updated on 8-May-2016
Official Symbol
Clip2provided by MGI
Official Full Name
CAP-GLY domain containing linker protein 2provided by MGI
Primary source
MGI:MGI:1313136
See related
Ensembl:ENSMUSG00000063146 Vega:OTTMUSG00000055745
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clip1; Cyln2; WSCR4; wbscr4; CLIP-115; mKIAA0291; B230327O20
Orthologs
Location:
5 G2; 5 74.63 cM
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (134489383..134552468, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (134965256..135028304, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene general transcription factor II I repeat domain-containing 1 Neighboring gene ribosomal protein S28 pseudogene Neighboring gene syncytin a Neighboring gene microRNA 7228 Neighboring gene replication factor C (activator 1) 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
microtubule plus-end binding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule plus-end binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with cytoplasmic microtubule IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
dendritic microtubule ISO
Inferred from Sequence Orthology
more info
 
lamellar body ISO
Inferred from Sequence Orthology
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with microtubule plus-end IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CAP-Gly domain-containing linker protein 2
Names
cytoplasmic linker protein 1, 115 kDa
cytoplasmic linker protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039162.2NP_001034251.1  CAP-Gly domain-containing linker protein 2 isoform b

    See identical proteins and their annotated locations for NP_001034251.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform b, which lacks an internal segment and is shorter, compared to isoform a.
    Source sequence(s)
    BC053048, BC121191
    Consensus CDS
    CCDS39309.1
    UniProtKB/Swiss-Prot
    Q9Z0H8
    Related
    ENSMUSP00000037431, OTTMUSP00000072583, ENSMUST00000036999, OTTMUST00000137943
    Conserved Domains (4) summary
    pfam10212
    Location:648836
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    pfam01302
    Location:222287
    CAP_GLY; CAP-Gly domain
    pfam10473
    Location:364451
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    TIGR02168
    Location:358980
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. NM_009990.3NP_034120.2  CAP-Gly domain-containing linker protein 2 isoform a

    See identical proteins and their annotated locations for NP_034120.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK045967, BC053048, BC121191
    Consensus CDS
    CCDS39310.1
    UniProtKB/Swiss-Prot
    Q9Z0H8
    Related
    ENSMUSP00000098212, OTTMUSP00000072584, ENSMUST00000100647, OTTMUST00000137944
    Conserved Domains (4) summary
    TIGR02132
    Location:380485
    phaR_Bmeg; polyhydroxyalkanoic acid synthase, PhaR subunit
    pfam10212
    Location:683871
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    COG1196
    Location:3571016
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01302
    Location:222287
    CAP_GLY; CAP-Gly domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    134489383..134552468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504427.2XP_006504490.1  

    Conserved Domains (4) summary
    TIGR02132
    Location:380485
    phaR_Bmeg; polyhydroxyalkanoic acid synthase, PhaR subunit
    COG5244
    Location:220854
    NIP100; Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning]
    pfam01302
    Location:222287
    CAP_GLY; CAP-Gly domain
    cl00223
    Location:700794
    NusB_Sun; RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the ...

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    131497082..131560139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)