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Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266682, updated on 17-May-2016
Official Symbol
Cyp3a2provided by RGD
Official Full Name
cytochrome P450, family 3, subfamily a, polypeptide 2provided by RGD
Primary source
RGD:708379
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Cyp3a11
Summary
catalyzes the conversion of testosterone to 6-beta-hydroxytestosterone [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Location:
12p11
Exon count:
12
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (11641500..11677818, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (13719927..13740743, complement)

Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene SMAD specific E3 ubiquitin protein ligase 1 Neighboring gene transformation/transcription domain-associated protein Neighboring gene cytochrome P450 3A1-like Neighboring gene similar to developmental pluripotency associated 4 isoform 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Clone Names

  • MGC108545

Gene Ontology Provided by RGD

Function Evidence Code Pubs
aromatase activity IEA
Inferred from Electronic Annotation
more info
 
caffeine oxidase activity ISO
Inferred from Sequence Orthology
more info
 
demethylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
heme binding IEA
Inferred from Electronic Annotation
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
iron ion binding ISO
Inferred from Sequence Orthology
more info
 
monooxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
monooxygenase activity ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity ISO
Inferred from Sequence Orthology
more info
 
steroid binding ISO
Inferred from Sequence Orthology
more info
 
steroid hydroxylase activity ISO
Inferred from Sequence Orthology
more info
 
testosterone 6-beta-hydroxylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
testosterone 6-beta-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
 
vitamin D 24-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
 
vitamin D3 25-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
alkaloid catabolic process ISO
Inferred from Sequence Orthology
more info
 
drug catabolic process ISO
Inferred from Sequence Orthology
more info
 
drug metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
drug metabolic process ISO
Inferred from Sequence Orthology
more info
 
exogenous drug catabolic process ISO
Inferred from Sequence Orthology
more info
 
heterocycle metabolic process ISO
Inferred from Sequence Orthology
more info
 
monoterpenoid metabolic process ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process ISO
Inferred from Sequence Orthology
more info
 
oxidative demethylation IDA
Inferred from Direct Assay
more info
PubMed 
oxidative demethylation ISO
Inferred from Sequence Orthology
more info
 
steroid catabolic process ISO
Inferred from Sequence Orthology
more info
 
steroid metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
cytochrome P450 3A2
Names
CYPIIIA2
P450-PCN2
P450/6-beta-A
cytochrome P450, family 3, subfamily a, polypeptide 11
cytochrome P450-PCN2
cytochrome P450/6-beta-A
testosterone 6-beta-hydroxylase
NP_695224.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153312.2NP_695224.2  cytochrome P450 3A2

    See identical proteins and their annotated locations for NP_695224.2

    Status: PROVISIONAL

    Source sequence(s)
    M13646
    UniProtKB/Swiss-Prot
    P05183
    Conserved Domains (1) summary
    pfam00067
    Location:39494
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

    Range
    11641500..11677818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000080.1 Alternate Rn_Celera

    Range
    10992673..11037068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)