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NAT9 N-acetyltransferase 9 (putative) [ Homo sapiens (human) ]

Gene ID: 26151, updated on 8-May-2016
Official Symbol
NAT9provided by HGNC
Official Full Name
N-acetyltransferase 9 (putative)provided by HGNC
Primary source
HGNC:HGNC:23133
See related
Ensembl:ENSG00000109065 HPRD:13259; Vega:OTTHUMG00000178870
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EBSP, hNATL
Orthologs
Location:
17q25.1
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 17 NC_000017.11 (74770547..74776395, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (72766686..72772534, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RAB37, member RAS oncogene family Neighboring gene CD300 molecule like family member f Neighboring gene uncharacterized LOC105371893 Neighboring gene SLC9A3 regulator 1 Neighboring gene microRNA 3615 Neighboring gene transmembrane protein 104 Neighboring gene glutamate ionotropic receptor NMDA type subunit 2C

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • DKFZp564C103

Gene Ontology Provided by GOA

Function Evidence Code Pubs
N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
N-terminal protein amino acid acetylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
protein complex IDA
Inferred from Direct Assay
more info
 
Preferred Names
N-acetyltransferase 9
Names
N-acetyltransferase 9 (GCN5-related, putative)
embryo brain specific protein
NP_056469.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305077.1NP_001292006.1  N-acetyltransferase 9 2

    See identical proteins and their annotated locations for NP_001292006.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in an internal exon, compared to variant 1. This variant encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    AC016888, BC004225, DA259097, HY222854
    Consensus CDS
    CCDS77102.1
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam00583
    Location:93161
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13161
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  2. NM_001305078.1NP_001292007.1  N-acetyltransferase 9 1

    See identical proteins and their annotated locations for NP_001292007.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants 1 and 3 encode the same protein (isoform 1).
    Source sequence(s)
    BC004195, BP231776, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam00583
    Location:94162
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13162
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  3. NM_001305079.1NP_001292008.1  N-acetyltransferase 9 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 3, which has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC004195, BP197633, DA259097, HY222854
    Consensus CDS
    CCDS77104.1
    UniProtKB/Swiss-Prot
    Q9BTE0
    UniProtKB/TrEMBL
    J3QL33
    Conserved Domains (1) summary
    pfam13302
    Location:13131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  4. NM_001305080.1NP_001292009.1  N-acetyltransferase 9 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1.
    Source sequence(s)
    BC004195, BM909550, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    UniProtKB/TrEMBL
    J3QQP3
    Conserved Domains (2) summary
    pfam00583
    Location:94157
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13157
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  5. NM_001305081.1NP_001292010.1  N-acetyltransferase 9 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) uses alternate in-frame splice sites in two exons, compared to variant 1. This results in a shorter protein (isoform 5), compared to isoform 1.
    Source sequence(s)
    BC004195, BU159218, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam00583
    Location:93160
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13160
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  6. NM_001305082.1NP_001292011.1  N-acetyltransferase 9 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) uses an alternate splice site in the 5' UTR, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (6) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AL537925, BC004195, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    UniProtKB/TrEMBL
    J3KT72
    Conserved Domains (2) summary
    pfam00583
    Location:99167
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:18167
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  7. NM_001305083.1NP_001292012.1  N-acetyltransferase 9 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) uses alternate in-frame splice sites in two exons, compared to variant 1. This results in a shorter protein (isoform 7), compared to isoform 1.
    Source sequence(s)
    BC004195, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam00583
    Location:93156
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13156
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  8. NM_001305084.1NP_001292013.1  N-acetyltransferase 9 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) lacks an exon and uses an alternate splice site in the 3'-most exon resulting in a translational frameshift, compared to variant 1. This variant encodes isoform 8 which is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    BC004195, DA010490, DA259097, HY222854
    Consensus CDS
    CCDS77103.1
    UniProtKB/Swiss-Prot
    Q9BTE0
    UniProtKB/TrEMBL
    J3KRQ7
    Conserved Domains (1) summary
    pfam13302
    Location:13132
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  9. NM_001305085.1NP_001292014.1  N-acetyltransferase 9 9

    See identical proteins and their annotated locations for NP_001292014.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) has multiple differences in the coding region, one of which results in a translational frameshift, compared to variant 1. The resulting protein (isoform 9) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    BC004195, DA259097, DB171198, HY222854
    Consensus CDS
    CCDS77101.1
    UniProtKB/Swiss-Prot
    Q9BTE0
    UniProtKB/TrEMBL
    J3KSE9
    Conserved Domains (1) summary
    pfam13302
    Location:13131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  10. NM_001305086.1NP_001292015.1  N-acetyltransferase 9 10

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) uses an alternate in-frame splice site in an internal exon and lacks an exon in the 3' coding region resulting in a translational frameshift, compared to variant 1. It encodes isoform 10 which has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC016888, BC004195, BX333236, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (1) summary
    pfam13302
    Location:13131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  11. NM_001305087.1NP_001292016.1  N-acetyltransferase 9 11

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) has multiple differences in the coding region and uses a downstream start codon, compared to variant 1. The resulting protein (isoform 11) has distinct N and C-termini and is shorter than isoform 1.
    Source sequence(s)
    AC016888, BC004195, BG702300, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam13302
    Location:3107
    Acetyltransf_3; Acetyltransferase (GNAT) domain
    cl17182
    Location:69106
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
  12. NM_001305088.1NP_001292017.1  N-acetyltransferase 9 12

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) has multiple differences in the coding region and uses a downstream start codon, compared to variant 1. The resulting protein (isoform 12) is shorter than isoform 1, has a shorter N-terminus and a distinct C-terminus.
    Source sequence(s)
    AC016888, BC004195, BQ068039, DA259097, HY222854
    UniProtKB/Swiss-Prot
    Q9BTE0
    Conserved Domains (2) summary
    pfam13302
    Location:1100
    Acetyltransf_3; Acetyltransferase (GNAT) domain
    cl17182
    Location:63100
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
  13. NM_015654.4NP_056469.2  N-acetyltransferase 9 1

    See identical proteins and their annotated locations for NP_056469.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    BC004195, DA259097, HY222854
    Consensus CDS
    CCDS11706.1
    UniProtKB/Swiss-Prot
    Q9BTE0
    Related
    ENSP00000350467, OTTHUMP00000260239, ENST00000357814, OTTHUMT00000443700
    Conserved Domains (2) summary
    pfam00583
    Location:94162
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13162
    Acetyltransf_3; Acetyltransferase (GNAT) domain

RNA

  1. NR_130953.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC004195, BI821280, DA259097, HY222854
  2. NR_130954.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15) contains an alternate internal exon and uses an alternate splice site in the 3'-most exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC004195, BM464121, DA259097, HY222854

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p2 Primary Assembly

    Range
    74770547..74776395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524609.1XP_011522911.1  

    Related
    ENSP00000462454, OTTHUMP00000260387, ENST00000583757, OTTHUMT00000443915
    Conserved Domains (1) summary
    pfam13302
    Location:13131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  2. XM_005257207.1XP_005257264.1  

    Related
    ENSP00000462019, OTTHUMP00000260240, ENST00000580301, OTTHUMT00000443703
    Conserved Domains (2) summary
    pfam00583
    Location:93161
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:13161
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  3. XM_011524608.1XP_011522910.1  

    Related
    ENSP00000462120, OTTHUMP00000260388, ENST00000582524, OTTHUMT00000443916
    Conserved Domains (1) summary
    pfam13302
    Location:13132
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  4. XM_005257212.3XP_005257269.1  

    See identical proteins and their annotated locations for XP_005257269.1

    Conserved Domains (2) summary
    pfam00583
    Location:63131
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:1131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  5. XM_006721813.2XP_006721876.1  

    See identical proteins and their annotated locations for XP_006721876.1

    Conserved Domains (2) summary
    pfam00583
    Location:63131
    Acetyltransf_1; Acetyltransferase (GNAT) family
    pfam13302
    Location:1131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  6. XM_011524610.1XP_011522912.1  

    Related
    ENSP00000463353, OTTHUMP00000260389, ENST00000583476, OTTHUMT00000443917
    Conserved Domains (1) summary
    pfam13302
    Location:13131
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  7. XM_011524607.1XP_011522909.1  

    Related
    ENSP00000464681, OTTHUMP00000260386, ENST00000584022, OTTHUMT00000443705
    Conserved Domains (1) summary
    pfam13302
    Location:13110
    Acetyltransf_3; Acetyltransferase (GNAT) domain
  8. XM_011524606.1XP_011522908.1  

RNA

  1. XR_934438.1 RNA Sequence

  2. XR_934436.1 RNA Sequence

  3. XR_243644.2 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018928.2 Alternate CHM1_1.1

    Range
    72831526..72837311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)