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AAR2 AAR2 splicing factor homolog [ Homo sapiens (human) ]

Gene ID: 25980, updated on 8-May-2016
Official Symbol
AAR2provided by HGNC
Official Full Name
AAR2 splicing factor homologprovided by HGNC
Primary source
HGNC:HGNC:15886
See related
Ensembl:ENSG00000131043 HPRD:12767; Vega:OTTHUMG00000032380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI-23; C20orf4
Summary
This gene encodes the homolog of the yeast A1-alpha2 repressin protein that is involved in mRNA splicing. Alternately spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Orthologs
Location:
20pter-q12
Exon count:
5
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 20 NC_000020.11 (36236417..36256941)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (34824339..34844863)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene erythrocyte membrane protein band 4.1 like 1 Neighboring gene uncharacterized LOC105372604 Neighboring gene uncharacterized LOC105372603 Neighboring gene uncharacterized LOC105372602 Neighboring gene discs large homolog associated protein 4 Neighboring gene DLGAP4 antisense RNA 1 Neighboring gene myosin light chain 9

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • bA234K24.2, DKFZp564N1363

Gene Ontology Provided by GOA

Process Evidence Code Pubs
spliceosomal tri-snRNP complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271874.1NP_001258803.1  protein AAR2 homolog

    See identical proteins and their annotated locations for NP_001258803.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AW006181, BC001751, HY019727
    Consensus CDS
    CCDS13273.1
    UniProtKB/Swiss-Prot
    Q9Y312
    Related
    ENSP00000313674, OTTHUMP00000178583, ENST00000320849, OTTHUMT00000276152
    Conserved Domains (3) summary
    pfam05282
    Location:20363
    AAR2; AAR2 protein
    cd13777
    Location:19148
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
  2. NM_015511.4NP_056326.2  protein AAR2 homolog

    See identical proteins and their annotated locations for NP_056326.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AW006181, BC019311, HY019727
    Consensus CDS
    CCDS13273.1
    UniProtKB/Swiss-Prot
    Q9Y312
    Related
    ENSP00000363043, OTTHUMP00000030846, ENST00000373932, OTTHUMT00000079001
    Conserved Domains (3) summary
    pfam05282
    Location:20363
    AAR2; AAR2 protein
    cd13777
    Location:19148
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p2 Primary Assembly

    Range
    36236417..36256941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011528762.1XP_011527064.1  

    See identical proteins and their annotated locations for XP_011527064.1

    UniProtKB/Swiss-Prot
    Q9Y312
    Conserved Domains (3) summary
    pfam05282
    Location:20363
    AAR2; AAR2 protein
    cd13777
    Location:19148
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
  2. XM_006723770.2XP_006723833.1  

    See identical proteins and their annotated locations for XP_006723833.1

    UniProtKB/Swiss-Prot
    Q9Y312
    Conserved Domains (3) summary
    pfam05282
    Location:20363
    AAR2; AAR2 protein
    cd13777
    Location:19148
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
  3. XM_011528763.1XP_011527065.1  

    See identical proteins and their annotated locations for XP_011527065.1

    UniProtKB/Swiss-Prot
    Q9Y312
    Conserved Domains (3) summary
    pfam05282
    Location:20363
    AAR2; AAR2 protein
    cd13777
    Location:19148
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 Alternate CHM1_1.1

    Range
    34726464..34746984
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)