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    GAPDH glyceraldehyde-3-phosphate dehydrogenase [ Homo sapiens (human) ]

    Gene ID: 2597, updated on 14-May-2013
    Official Symbol
    GAPDHprovided by HGNC
    Official Full Name
    glyceraldehyde-3-phosphate dehydrogenaseprovided by HGNC
    Primary source
    HGNC:4141
    Locus tag
    CDABP0047
    See related
    Ensembl:ENSG00000111640; HPRD:00713; MIM:138400; Vega:OTTHUMG00000137379
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    G3PD; GAPD
    Summary
    The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
    Location :
    12p13
    Sequence :
    Chromosome: 12; NC_000012.11 (6643585..6647537)
    See GAPDH in Epigenomics, MapViewer

    Chromosome 12 - NC_000012.11Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L51 Neighboring gene non-SMC condensin I complex, subunit D2 Neighboring gene small Cajal body-specific RNA 10 Neighboring gene uncharacterized LOC100996356 Neighboring gene intermediate filament family orphan 1 Neighboring gene NOP2 nucleolar protein

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Protein Gene Interaction Pubs
    Rev, p19 rev HIV-1 Rev interacting protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with GAPDH is increased by RRE PubMed

    Go to the HIV-1, Human Protein Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description
    NP_002037.2 NP_006363.3 SYNCRIP    BIND  PubMed NSAP-1 interacts with GAPDH. 
    P04406 P60709 ACTB    HPRD  PubMed  
    P04406 P05067 APP    HPRD  PubMed  
    P04406 P10275 AR    HPRD  PubMed  
    P04406 ADP ribosylation factor related protein 2 ARL15    HPRD  PubMed  
    P04406 P54259 ATN1    HPRD  PubMed  
    P04406 P54253 ATXN1    HPRD  PubMed  
    P04406 P07738 BPGM    HPRD  PubMed  
    P04406 Q9BX70 BTBD2    HPRD  PubMed  
    P04406 Q14012 CAMK1    HPRD  PubMed  
    P04406 Q13554 CAMK2B    HPRD  PubMed  
    P04406 Q16566 CAMK4    HPRD  PubMed  
    P04406 Q99653 CHP1    HPRD  PubMed  
    P04406 P63167 DYNLL1    HPRD  PubMed  
    P04406 P00533 EGFR    HPRD  PubMed  
    P04406 O75344 FKBP6    HPRD  PubMed  
    P04406 P04406 GAPDH    HPRD  PubMed  
    P04406 Q13255 GRM1    HPRD  PubMed  
    P04406 Q14541 HNF4G    HPRD  PubMed  
    P04406 P42858 HTT    HPRD  PubMed  
    P04406 Q92993 KAT5    HPRD  PubMed  
    P04406 Q16363 LAMA4    HPRD  PubMed  
    P04406 O43504 LAMTOR5    HPRD  PubMed  
    P04406 Q99972 MYOC    HPRD  PubMed  
    P04406 Q96RI1 NR1H4    HPRD  PubMed  
    P04406 Q15102 PAFAH1B3    HPRD  PubMed  
    P04406 Q9UN74 PCDHA4    HPRD  PubMed  
    P04406 Q13087 PDIA2    HPRD  PubMed  
    P04406 P00558 PGK1    HPRD  PubMed  
    P04406 O14939 PLD2    HPRD  PubMed  
    P04406 Protein phosphatase 1E PPM1E    HPRD  PubMed  
    P04406 Q06830 PRDX1    HPRD  PubMed  
    P04406 P41743 PRKCI    HPRD  PubMed  
    P04406 O00231 PSMD11    HPRD  PubMed  
    P04406 P61019 RAB2A    HPRD  PubMed  
    P04406 P15927 RPA2    HPRD  PubMed  
    P04406 P06703 S100A6    HPRD  PubMed  
    P04406 P50453 SERPINB9    HPRD  PubMed  
    P04406 Q8IUQ4 SIAH1    HPRD  PubMed  
    P04406 P11166 SLC2A1    HPRD  PubMed  
    P04406 P14672 SLC2A4    HPRD  PubMed  
    P04406 Q6EEV6 SUMO4    HPRD  PubMed  
    P04406 P04183 TK1    HPRD  PubMed  
    P04406 O94811 TPPP    HPRD  PubMed  
    BioGRID:108868 BioGRID:122379 ACD    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:116460 ACOT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:106585 ACTC1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:106710 AKT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:106798 ANXA1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:106807 ANXA7    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:107587 AP2M1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:106848 APP    BioGRID  PubMed Reconstituted Complex 
    BioGRID:108868 BioGRID:106862 AR    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:108868 BioGRID:120080 ARL15    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:106902 ARRB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107776 ATF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108156 ATN1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:112217 ATXN1    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:108868 BioGRID:107106 BID    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:120778 BTBD2    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:107160 BTK    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:120937 CAND1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107276 CAPNS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107315 CBL    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107332 CCNB1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:108868 BioGRID:107358 CD4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107452 CDK2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107460 CDKN1A    BioGRID  PubMed Affinity Capture-MS; Reconstituted Complex 
    BioGRID:108868 BioGRID:107463 CDKN2A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:116183 COPS5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:116176 COPS6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107816 CRYZ    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:107861 CSTF3    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:114032 CUL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:114031 CUL2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:114030 CUL3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:114028 CUL4B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:118787 DCPS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108040 DFFA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108237 EEF1A1    BioGRID  PubMed Affinity Capture-MS; Co-fractionation 
    BioGRID:108868 BioGRID:108338 ENO1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:108347 EP300    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:108403 ESR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:116175 FERMT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108621 FN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108014 GADD45A    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:108868 GAPDH    BioGRID  PubMed Co-crystal Structure; Two-hybrid 
    BioGRID:108868 BioGRID:114094 GAS7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108903 GBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108964 GJA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109068 GOT2    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:109142 GRB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109187 GSK3B    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:109514 HES1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:109416 HNF4G    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:128670 HNRNPA3    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:109552 HSP90AA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109558 HSP90AB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109537 HSPA1L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109545 HSPA9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109561 HSPD1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:109314 HTT    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:115015 IQCB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:114995 ISG15    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:109883 ITGA4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:109938 KARS    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:115779 KAT5    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:115326 KCNE3    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:115114 KIAA0101    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:110104 LAMA4    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:115796 LAMTOR5    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:110169 LIG4    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111580 MAPK1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:118166 MAT2B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:110358 MDM2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:116184 METAP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:110736 MYOC    BioGRID  PubMed Far Western; Two-hybrid 
    BioGRID:108868 BioGRID:204968 Mapk13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:110815 NEDD8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:110868 NFYC    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:110924 NPAT    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:110929 NPM1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:115296 NR1H4    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:118917 OLA1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:114617 OSMR    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:117747 OSTF1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:113777 PABPN1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:111087 PAFAH1B3    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111105 PARK2    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:121084 PCDHA4    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111142 PCNA    BioGRID  PubMed Affinity Capture-MS; Reconstituted Complex 
    BioGRID:108868 BioGRID:122240 PDIA2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:108868 BioGRID:111244 PGAM1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:111251 PGK1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:111332 PKM    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:111354 PLD2    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:108868 BioGRID:117417 POT1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111447 POU2F1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:108868 BioGRID:111448 POU2F2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:108868 BioGRID:111456 POU5F1    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:108868 BioGRID:111475 PPIB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111512 PPP2R2A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111528 PPP5C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111089 PRDX1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111570 PRKCI    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:108868 BioGRID:111578 PRKG1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:120792 PRPF40A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111642 PSEN1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111657 PSMA3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111689 PSMD11    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111719 PTK2    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:123869 QRICH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:111845 RAP1GDS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:115480 RBM5    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:112038 RPA2    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:111290 SERPINB9    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:112316 SET    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:108868 BioGRID:112372 SIAH1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:116983 SIRT1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:108868 BioGRID:112408 SLC2A4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:108868 BioGRID:112490 SMN1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:112506 SNCA    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:116162 STIP1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:113188 SUMO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:112497 SUMO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:132223 SUMO4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:112872 TERF1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:117660 TINF2    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:112938 TK1    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:113010 TP53    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:108868 BioGRID:113020 TPI1    BioGRID  PubMed Co-fractionation 
    BioGRID:108868 BioGRID:113603 TUBA1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:124259 TUBA1C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:128444 TUBB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:113135 TUFM    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:113146 TXN    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:108219 TYMP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:119007 UBQLN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:118895 USP25    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:113255 VCAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:113363 YWHAE    BioGRID  PubMed Two-hybrid 
    BioGRID:108868 BioGRID:113364 YWHAG    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:116168 YWHAQ    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:108868 BioGRID:1205542 rev    BioGRID  PubMed Affinity Capture-MS 

    Markers

    Homology

    Clone Names

    • MGC88685

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    NADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    peptidyl-cysteine S-nitrosylase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    carbohydrate metabolic process TAS
    Traceable Author Statement
    more info
     
    cellular response to interferon-gamma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    gluconeogenesis TAS
    Traceable Author Statement
    more info
     
    glucose metabolic process TAS
    Traceable Author Statement
    more info
     
    glycolysis IEA
    Inferred from Electronic Annotation
    more info
     
    glycolysis NAS
    Non-traceable Author Statement
    more info
     
    glycolysis TAS
    Traceable Author Statement
    more info
     
    microtubule cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of translation IDA
    Inferred from Direct Assay
    more info
     
    negative regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    peptidyl-cysteine S-trans-nitrosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    small molecule metabolic process TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm NAS
    Non-traceable Author Statement
    more info
     
    cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytosol TAS
    Traceable Author Statement
    more info
     
    extracellular vesicular exosome IDA
    Inferred from Direct Assay
    more info
     
    lipid particle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
     
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    glyceraldehyde-3-phosphate dehydrogenase
    Names
    glyceraldehyde-3-phosphate dehydrogenase
    aging-associated gene 9 protein
    peptidyl-cysteine S-nitrosylase GAPDH
    NP_001243728.1
    NP_002037.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_007073.2 RefSeqGene

      Range
      4929..8881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001256799.1NP_001243728.1  glyceraldehyde-3-phosphate dehydrogenase isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      BC009081, BG724119, BI463134
      Consensus CDS
      CCDS58201.1
      UniProtKB/TrEMBL
      E7EUT4
      UniProtKB/Swiss-Prot
      P04406
      Related
      ENSP00000380067, OTTHUMP00000174434, ENST00000396858, OTTHUMT00000268066
      Conserved Domains (2) summary
      pfam00044
      Location:1109
      Blast Score: 468
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:115272
      Blast Score: 706
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
    2. NM_002046.4NP_002037.2  glyceraldehyde-3-phosphate dehydrogenase isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      BC009081, BU155402
      Consensus CDS
      CCDS8549.1
      UniProtKB/Swiss-Prot
      P04406
      Related
      ENSP00000380070, OTTHUMP00000174431, ENST00000396861, OTTHUMT00000268060
      Conserved Domains (3) summary
      PTZ00023
      Location:4335
      Blast Score: 1345
      PTZ00023; glyceraldehyde-3-phosphate dehydrogenase; Provisional
      smart00846
      Location:4152
      Blast Score: 616
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:157314
      Blast Score: 705
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000012.11 Reference GRCh37.p10 Primary Assembly

      Range
      6643585..6647537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000144.1 Alternate HuRef

      Range
      6497829..6501781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018923.1 Alternate CHM1_1.0

      Range
      6574947..6578899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

      Supplemental Content

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