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THUMPD3 THUMP domain containing 3 [ Homo sapiens (human) ]

Gene ID: 25917, updated on 8-May-2016
Official Symbol
THUMPD3provided by HGNC
Official Full Name
THUMP domain containing 3provided by HGNC
Primary source
HGNC:HGNC:24493
See related
Ensembl:ENSG00000134077 HPRD:15507; Vega:OTTHUMG00000097031
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
3p25.3
Exon count:
12
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (9362976..9386791)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (9404660..9428475)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene SLIT-ROBO Rho GTPase activating protein 3 Neighboring gene uncharacterized LOC101927440 Neighboring gene phosphoglycerate mutase 1 pseudogene 4 Neighboring gene THUMPD3 antisense RNA 1 Neighboring gene SET domain containing 5

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp434F091

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
Preferred Names
THUMP domain-containing protein 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114092.1NP_001107564.1  THUMP domain-containing protein 3

    See identical proteins and their annotated locations for NP_001107564.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC018506, AK001680, AL117483, DA713744
    Consensus CDS
    CCDS2573.1
    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Related
    ENSP00000395893, OTTHUMP00000207149, ENST00000452837, OTTHUMT00000338127
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  2. NM_015453.2NP_056268.2  THUMP domain-containing protein 3

    See identical proteins and their annotated locations for NP_056268.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC018506, AK001680, AL117483, DA713744
    Consensus CDS
    CCDS2573.1
    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Related
    ENSP00000339532, OTTHUMP00000122526, ENST00000345094, OTTHUMT00000214127
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

    Range
    9362976..9386791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005265021.3XP_005265078.1  

    See identical proteins and their annotated locations for XP_005265078.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  2. XM_011533571.1XP_011531873.1  

    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    cl17173
    Location:317416
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  3. XM_005265024.3XP_005265081.1  

    See identical proteins and their annotated locations for XP_005265081.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  4. XM_005265022.3XP_005265079.1  

    See identical proteins and their annotated locations for XP_005265079.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Related
    ENSP00000424064, OTTHUMP00000207150, ENST00000515662, OTTHUMT00000338128
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  5. XM_005265023.2XP_005265080.1  

    See identical proteins and their annotated locations for XP_005265080.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  6. XM_006713086.2XP_006713149.1  

    See identical proteins and their annotated locations for XP_006713149.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020
  7. XM_011533570.1XP_011531872.1  

    See identical proteins and their annotated locations for XP_011531872.1

    UniProtKB/Swiss-Prot
    Q9BV44
    UniProtKB/TrEMBL
    A0A024R2F4
    Conserved Domains (2) summary
    cd11715
    Location:40286
    THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
    pfam01170
    Location:293478
    UPF0020; Putative RNA methylase family UPF0020

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 Alternate CHM1_1.1

    Range
    9354927..9378706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)