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MGAT4C MGAT4 family member C [ Homo sapiens (human) ]

Gene ID: 25834, updated on 7-May-2016
Official Symbol
MGAT4Cprovided by HGNC
Official Full Name
MGAT4 family member Cprovided by HGNC
Primary source
HGNC:HGNC:30871
See related
Ensembl:ENSG00000182050 HPRD:09575; MIM:607385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GNTIVH; HGNT-IV-H
Orthologs
Location:
12q21
Exon count:
15
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (85976235..86838904, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (86373037..87232681, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 9 Neighboring gene neurotensin Neighboring gene uncharacterized LOC105369877 Neighboring gene uncharacterized LOC105369878 Neighboring gene ribosomal protein L23a pseudogene 68

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp160, precursor env Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus PubMed
Envelope transmembrane glycoprotein gp41 env Mannose-containing, N-linked oligosaccharide side-chains of HIV-1 gp41 are involved in the initial stage of infection by HIV-1; glycosylation inhibitors block virus-cell and cell-cell fusion and release of the virions PubMed

Go to the HIV-1, Human Interaction Database

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS
Traceable Author Statement
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
N-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
Golgi membrane TAS
Traceable Author Statement
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
Names
MGAT4 family, member C
N-acetylglucosaminyltransferase IV homolog
N-acetylglucosaminyltransferase IVc
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc
UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc
UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV
UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog
glcNAc-T IVc
gnT-IVc
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
NP_037376.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013244.3NP_037376.2  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

    See identical proteins and their annotated locations for NP_037376.2

    Status: VALIDATED

    Source sequence(s)
    BC035851, BC064141, BI667691, DA795621
    Consensus CDS
    CCDS9030.1
    UniProtKB/Swiss-Prot
    Q9UBM8
    Related
    ENSP00000478300, OTTHUMP00000276095, ENST00000621808, OTTHUMT00000406225
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    85976235..86838904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011538159.1XP_011536461.1  

    See identical proteins and their annotated locations for XP_011536461.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  2. XM_011538154.1XP_011536456.1  

    See identical proteins and their annotated locations for XP_011536456.1

    Conserved Domains (1) summary
    pfam04666
    Location:58333
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  3. XM_011538158.1XP_011536460.1  

    See identical proteins and their annotated locations for XP_011536460.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  4. XM_011538152.1XP_011536454.1  

    See identical proteins and their annotated locations for XP_011536454.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:84359
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  5. XM_011538153.1XP_011536455.1  

    See identical proteins and their annotated locations for XP_011536455.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:84359
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  6. XM_011538151.1XP_011536453.1  

    See identical proteins and their annotated locations for XP_011536453.1

    Conserved Domains (1) summary
    pfam04666
    Location:93368
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  7. XM_011538157.1XP_011536459.1  

    See identical proteins and their annotated locations for XP_011536459.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Related
    ENSP00000477650, OTTHUMP00000276094, ENST00000620241, OTTHUMT00000406212
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  8. XM_005268776.3XP_005268833.1  

    See identical proteins and their annotated locations for XP_005268833.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:84359
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  9. XM_011538149.1XP_011536451.1  

    Conserved Domains (1) summary
    pfam04666
    Location:104379
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  10. XM_011538156.1XP_011536458.1  

    See identical proteins and their annotated locations for XP_011536458.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  11. XM_005268779.2XP_005268836.1  

    See identical proteins and their annotated locations for XP_005268836.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Related
    ENSP00000446647, OTTHUMP00000242279, ENST00000552808, OTTHUMT00000406215
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  12. XM_011538150.1XP_011536452.1  

    See identical proteins and their annotated locations for XP_011536452.1

    Conserved Domains (1) summary
    pfam04666
    Location:93368
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  13. XM_011538155.1XP_011536457.1  

    See identical proteins and their annotated locations for XP_011536457.1

    Conserved Domains (1) summary
    pfam04666
    Location:58333
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  14. XM_011538160.1XP_011536462.1  

    See identical proteins and their annotated locations for XP_011536462.1

    UniProtKB/Swiss-Prot
    Q9UBM8
    Conserved Domains (1) summary
    pfam04666
    Location:55330
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    86338018..87197963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)