Format

Send to:

Choose Destination

Cpt1a carnitine palmitoyltransferase 1A [ Rattus norvegicus (Norway rat) ]

Gene ID: 25757, updated on 8-May-2016
Official Symbol
Cpt1aprovided by RGD
Official Full Name
carnitine palmitoyltransferase 1Aprovided by RGD
Primary source
RGD:2396
See related
Ensembl:ENSRNOG00000014254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
CPT-Ia
Summary
enzyme that catalyses the transfer of long chain fatty acids to carnitine for translocation across the mitochondrial inner membrane [RGD, Feb 2006]
Orthologs
Location:
1q43
Exon count:
20
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (218568232..218629679)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (225436031..225497586)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene immunoglobulin mu binding protein 2 Neighboring gene mitochondrial ribosomal protein L21 Neighboring gene uncharacterized LOC102550887 Neighboring gene testis expressed metallothionein like protein Neighboring gene galanin and GMAP prepropeptide

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
carnitine O-palmitoyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
carnitine O-palmitoyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
carnitine O-palmitoyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
carnitine O-palmitoyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
palmitoleoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
palmitoleoyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
carnitine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
carnitine metabolic process ISO
Inferred from Sequence Orthology
more info
 
carnitine metabolic process TAS
Traceable Author Statement
more info
PubMed 
cellular response to fatty acid IEP
Inferred from Expression Pattern
more info
PubMed 
eating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
 
glucose metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-chain fatty acid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
long-chain fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-chain fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
long-chain fatty acid metabolic process TAS
Traceable Author Statement
more info
PubMed 
positive regulation of fatty acid beta-oxidation IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein homooligomerization IDA
Inferred from Direct Assay
more info
PubMed 
regulation of fatty acid beta-oxidation TAS
Traceable Author Statement
more info
PubMed 
regulation of fatty acid oxidation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of insulin secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
NOT endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
carnitine O-palmitoyltransferase 1, liver isoform
Names
CPT I
CPT1-L
CPTI-L
Carnitine palmitoyltransferase 1 alpha, liver isoform
carnitine O-palmitoyltransferase I, liver isoform
carnitine palmitoyltransferase 1, liver
carnitine palmitoyltransferase 1a, liver
NP_113747.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031559.2NP_113747.2  carnitine O-palmitoyltransferase 1, liver isoform

    See identical proteins and their annotated locations for NP_113747.2

    Status: VALIDATED

    Source sequence(s)
    AA875270, BC072522
    UniProtKB/Swiss-Prot
    P32198
    Related
    ENSRNOP00000019652, ENSRNOT00000019652
    Conserved Domains (1) summary
    pfam00755
    Location:170763
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    218568232..218629679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230695.1XP_006230757.1  

    See identical proteins and their annotated locations for XP_006230757.1

    UniProtKB/Swiss-Prot
    P32198
    Conserved Domains (1) summary
    pfam00755
    Location:170763
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    198121771..198182510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)