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Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25642, updated on 26-May-2016
Official Symbol
Cyp3a23/3a1provided by RGD
Official Full Name
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1provided by RGD
Primary source
RGD:628626
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
CYP; RL33; cDEX; Cyp3a1; Cyp3a3; CYP3A23
Summary
steroid-inducible member of p450 subfamily 3A; induced by pregnenolone 16 alpha-carbonitrile, dexamethasone (DEX), phenobarbital (PB) and triacetyloleandomycin [RGD, Feb 2006]
See Cyp3a23/3a1 in Genome Data Viewer Map Viewer
Location:
12p11
Exon count:
13
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (11053888..11082742, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (13145742..13174596, complement)

Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L29-like Neighboring gene pumilio domain-containing protein KIAA0020 homolog Neighboring gene uncharacterized LOC103693618 Neighboring gene similar to developmental pluripotency associated 4 isoform 1 Neighboring gene zinc finger and SCAN domain-containing protein 25 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC108757

Gene Ontology Provided by RGD

Process Evidence Code Pubs
aging IEP
Inferred from Expression Pattern
more info
PubMed 
drug metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
oxidative demethylation IDA
Inferred from Direct Assay
more info
PubMed 
response to cadmium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucocorticoid IEP
Inferred from Expression Pattern
more info
PubMed 
response to metal ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to nutrient IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
cytochrome P450 3A1
Names
CYPIIIA1
Cytochrome P450, subfamily IIIA, polypeptide 3
P450 IIIA
P450-PCN1
cytochrome P-450PCN (PNCN inducible)
cytochrome P450, family 3, subfamily a, polypeptide 1
cytochrome P450, subfamily 3A, polypeptide 3
cytochrome P450-PCN1
cytochrome P450/6 beta B
NP_037237.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013105.2NP_037237.2  cytochrome P450 3A1

    See identical proteins and their annotated locations for NP_037237.2

    Status: PROVISIONAL

    Source sequence(s)
    BC088163
    UniProtKB/TrEMBL
    Q06884
    Conserved Domains (1) summary
    pfam00067
    Location:39492
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

    Range
    11053888..11082742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000080.1 Alternate Rn_Celera

    Range
    11063015..11090937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)