BCL6B B-cell CLL/lymphoma 6, member B [Homo sapiens] - Gene

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Summary

Official Symbol: BCL6Bprovided by HGNC
Official Full Name: B-cell CLL/lymphoma 6, member Bprovided by HGNC
Primary source: HGNC:1002
See related: Ensembl:ENSG00000161940; HPRD:16414; MIM:608992
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: BAZF; ZNF62; ZBTB28

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Genomic context

Location :: 17p13.1

Sequence :: Chromosome: 17; NC_000017.10 (6926369..6932961)

See BCL6B in Epigenomics, MapViewer

Chromosome 17 - NC_000017.10 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Products	Interactant	Other Gene	Source	Pubs	Description
Q8N143	P41182	BCL6	HPRD	PubMed
BioGRID:129125	BioGRID:107076	BCL6	BioGRID	PubMed	Reconstituted Complex; Two-hybrid
BioGRID:129125	BioGRID:109315	HDAC1	BioGRID	PubMed	Two-hybrid
BioGRID:129125	BioGRID:117439	SIN3A	BioGRID	PubMed	Two-hybrid

Function	Evidence Code	Pubs
DNA binding	IEA Inferred from Electronic Annotation more info
metal ion binding	IEA Inferred from Electronic Annotation more info
zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
negative regulation of transcription from RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
intracellular	IEA Inferred from Electronic Annotation more info
nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: B-cell CLL/lymphoma 6 member B protein

Names: B-cell CLL/lymphoma 6 member B protein; zinc finger protein 62; bcl6-associated zinc finger protein; B-cell CLL/lymphoma 6, member B (zinc finger protein)

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_181844.3 → NP_862827.1 B-cell CLL/lymphoma 6 member B protein

Status: VALIDATED

Source sequence(s)

AB076580, BC059404

Consensus CDS

CCDS42248.1

UniProtKB/TrEMBL

A8KA13

UniProtKB/Swiss-Prot

Q8N143

Related

ENSP00000293805, ENST00000293805

Conserved Domains (2) summary

pfam13465
Location:371 – 396
Blast Score: 101

zf-H2C2_2; Zinc-finger double domain

cl02518
Location:28 – 132
Blast Score: 247

BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000017.10 Reference GRCh37.p5 Primary Assembly

Range

6926369..6932961

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000149.1 Alternate HuRef

Range

6820015..6826661

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AB076581.1	BAC00963.1
genomic	AC040977.10 (147892..154484)	None
genomic	CH471108.2	EAW90273.1
		EAW90274.1
genomic	M88371.1	AAA61329.1
mRNA	AB076580.1	BAC00962.1
mRNA	AK024695.1	None
mRNA	AK122893.1	BAG53785.1
mRNA	AK292878.1	BAF85567.1
mRNA	AK293102.1	BAF85791.1
mRNA	BC059404.1	AAH59404.1
other-genetic	EU446594.1	ABZ92123.1