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pop1 cullin 1 adaptor protein Pop1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540511, updated on 11-Apr-2024

Summary

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Gene symbol
pop1
Gene description
cullin 1 adaptor protein Pop1
Primary source
PomBase:SPBC1718.01
Locus tag
SPBC1718.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC2G2.18; ste16
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Genomic context

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Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3469096..3471885)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative 2' O-ribose methyltransferase Mrm2 Neighboring gene putative mannose-6-phosphate isomerase Neighboring gene putative beta-glucosidase Psu2 Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene synaptonemal complex-associated protein hop1 Neighboring gene putative glycerol-3-phosphate O-acyltransferase Neighboring gene DNA-directed RNA polymerase I complex subunit Ker1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Ste16 WD-repeat protein regulates cell-cycle progression under starvation through the Rum1 protein in Schizosaccharomyces pombe. Maekawa H, et al. Curr Genet, 1998 Jan. PMID 9472077
  2. Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. Osaka F, et al. EMBO J, 2000 Jul 3. PMID 10880460, Free PMC Article
  3. Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase. Kominami K, et al. Genes Cells, 1998 Nov. PMID 9990507
  4. The Protein Level of Rev1, a TLS Polymerase in Fission Yeast, Is Strictly Regulated during the Cell Cycle and after DNA Damage. Uchiyama M, et al. PLoS One, 2015. PMID 26147350, Free PMC Article
  5. Requirement of the SCFPop1/Pop2 Ubiquitin Ligase for Degradation of the Fission Yeast S Phase Cyclin Cig2. Yamano H, et al. J Biol Chem, 2004 Apr 30. PMID 14970237

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin-like ligase-substrate adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in anaphase-promoting complex-dependent catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nuclear SCF ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
cullin 1 adaptor protein Pop1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3469096..3471885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355815.1 → NP_001342944.1  cullin 1 adaptor protein Pop1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87060, Q9P7P3
    Conserved Domains (3) summary
    cd00200
    Location:409 → 725
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:409 → 444
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:305 → 346
    F-box-like; F-box-like
Nucleotide Protein
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