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ETFBKMT electron transfer flavoprotein beta subunit lysine methyltransferase [ Homo sapiens (human) ]

Gene ID: 254013, updated on 8-May-2016
Official Symbol
ETFBKMTprovided by HGNC
Official Full Name
electron transfer flavoprotein beta subunit lysine methyltransferaseprovided by HGNC
Primary source
HGNC:HGNC:28739
See related
Ensembl:ENSG00000139160 HPRD:14666; MIM:615256; Vega:OTTHUMG00000169085
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
METTL20; C12orf72; ETFB-KMT
Orthologs
Location:
12p11.21
Exon count:
6
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (31647160..31669086)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (31800094..31822016)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene DENND5B antisense RNA 1 Neighboring gene ribosomal protein L31 pseudogene 50 Neighboring gene adenylate kinase 4 pseudogene 3 Neighboring gene antagonist of mitotic exit network 1 homolog Neighboring gene uncharacterized LOC105369722 Neighboring gene stathmin 1 pseudogene 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC50559

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein-lysine N-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
electron transfer flavoprotein beta subunit lysine methyltransferase
Names
ETFB lysine methyltransferase
methyltransferase like 20
methyltransferase-like protein 20
protein N-lysine methyltransferase METTL20
NP_001129335.1
NP_001129336.1
NP_776163.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135863.1NP_001129335.1  electron transfer flavoprotein beta subunit lysine methyltransferase

    See identical proteins and their annotated locations for NP_001129335.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different segment for its 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AC023157, BC039107, BC039417, DA303137
    Consensus CDS
    CCDS8724.1
    UniProtKB/Swiss-Prot
    Q8IXQ9
    Related
    ENSP00000350353, OTTHUMP00000240056, ENST00000357721, OTTHUMT00000402196
    Conserved Domains (1) summary
    cd02440
    Location:119206
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  2. NM_001135864.1NP_001129336.1  electron transfer flavoprotein beta subunit lysine methyltransferase

    See identical proteins and their annotated locations for NP_001129336.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses a different segment for its 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AC023157, AK290248, BC039417
    Consensus CDS
    CCDS8724.1
    UniProtKB/Swiss-Prot
    Q8IXQ9
    Related
    ENSP00000396123, OTTHUMP00000240053, ENST00000412352, OTTHUMT00000402193
    Conserved Domains (1) summary
    cd02440
    Location:119206
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  3. NM_173802.3NP_776163.1  electron transfer flavoprotein beta subunit lysine methyltransferase

    See identical proteins and their annotated locations for NP_776163.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AC023157, BC039417, BC039535
    Consensus CDS
    CCDS8724.1
    UniProtKB/Swiss-Prot
    Q8IXQ9
    Related
    ENSP00000379112, OTTHUMP00000240054, ENST00000395763, OTTHUMT00000402194
    Conserved Domains (1) summary
    cd02440
    Location:119206
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    31647160..31669086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719060.2XP_006719123.1  

    See identical proteins and their annotated locations for XP_006719123.1

    UniProtKB/Swiss-Prot
    Q8IXQ9
    Related
    ENSP00000441421, OTTHUMP00000240055, ENST00000538463, OTTHUMT00000402195
    Conserved Domains (1) summary
    cd02440
    Location:119206
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    31765730..31787988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)