These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_012889.2 RefSeqGene
- Range
- 4979..19740
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001170634.1 → NP_001164105.1 RNA-binding protein FUS isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter isoform (2), compared to isoform 1.
- Source sequence(s)
-
AC009088, AI333366, DC361263
- UniProtKB/Swiss-Prot
-
P35637
- Related
- ENSP00000369594, OTTHUMP00000255007, ENST00000380244, OTTHUMT00000433551
- Conserved Domains (2) summary
-
- cd00590
Location:285 – 367
Blast Score: 163
- RRM; RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA ...
- cl02656
Location:425 – 448
Blast Score: 87
- zf-RanBP; Zn-finger in Ran binding protein and others
-
NM_001170937.1 → NP_001164408.1 RNA-binding protein FUS isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.
- Source sequence(s)
-
AC009088, AI333366, DA541747, DC361263, U36561
- UniProtKB/TrEMBL
-
Q13344
- Related
- ENSP00000378041, ENST00000394533
- Conserved Domains (2) summary
-
- cd00590
Location:282 – 364
Blast Score: 163
- RRM; RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA ...
- cl02656
Location:422 – 445
Blast Score: 87
- zf-RanBP; Zn-finger in Ran binding protein and others
-
NM_004960.3 → NP_004951.1 RNA-binding protein FUS isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AC009088, AI333366, AW408771, BC002459, DC361263
- Consensus CDS
-
CCDS10707.1
- UniProtKB/Swiss-Prot
-
P35637
- UniProtKB/TrEMBL
-
Q6IBQ5
- Related
- ENSP00000254108, OTTHUMP00000163228, ENST00000254108, OTTHUMT00000255526
- Conserved Domains (2) summary
-
- cd00590
Location:286 – 368
Blast Score: 163
- RRM; RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA ...
- cl02656
Location:426 – 449
Blast Score: 87
- zf-RanBP; Zn-finger in Ran binding protein and others
RNA
-
NR_028388.2 RNA Sequence
- Description
- Transcript Variant: This variant (2) omits an exon in the coding sequence, compared to variant 1, resulting in a frameshift and premature stop codon. The transcript is predicted to be subject to nonsense-mediated decay and thus the truncated protein is not annotated.
- Source sequence(s)
-
AC009088, AI333366, AW408771, DC361263
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000016.9 Reference GRCh37.p5 Primary Assembly
- Range
- 31191431..31206192
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000148.1 Alternate HuRef
- Range
- 28753052..28767812
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_001010850.1: Suppressed sequence
- Description
- NM_001010850.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.