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Mas1 MAS1 proto-oncogene, G protein-coupled receptor [ Rattus norvegicus (Norway rat) ]

Gene ID: 25153, updated on 17-May-2016
Official Symbol
Mas1provided by RGD
Official Full Name
MAS1 proto-oncogene, G protein-coupled receptorprovided by RGD
Primary source
RGD:3049
See related
Ensembl:ENSRNOG00000014971
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Mgra; c-mas
Summary
oncogene; may be involved in function or development of neural tissues [RGD, Feb 2006]
Location:
1q11-q12
Exon count:
6
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (48076768..48108218)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (51644462..51675365, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene PARN like, ribonuclease domain containing 1 Neighboring gene MAS-related GPR, member H Neighboring gene uncharacterized LOC103690970 Neighboring gene uncharacterized LOC103690971 Neighboring gene uncharacterized LOC102553394

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G-protein coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
angiotensin receptor activity IEA
Inferred from Electronic Annotation
more info
 
angiotensin receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
angiotensin receptor activity ISO
Inferred from Sequence Orthology
more info
 
peptide binding IEA
Inferred from Electronic Annotation
more info
 
peptide binding ISO
Inferred from Sequence Orthology
more info
 
peptide hormone binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
activation of NF-kappaB-inducing kinase activity IEA
Inferred from Electronic Annotation
more info
 
activation of NF-kappaB-inducing kinase activity ISO
Inferred from Sequence Orthology
more info
 
angiotensin-activated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
cellular response to peptide hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
hippocampus development IEP
Inferred from Expression Pattern
more info
PubMed 
male gonad development IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA replication IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of inositol phosphate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase C signaling IEA
Inferred from Electronic Annotation
more info
 
protein kinase C signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 
regulation of inflammatory response ISO
Inferred from Sequence Orthology
more info
 
response to activity IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to gonadotropin IEP
Inferred from Expression Pattern
more info
PubMed 
response to peptide hormone IEP
Inferred from Expression Pattern
more info
PubMed 
spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
intracellular IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
proto-oncogene Mas
Names
MAS proto-oncogene
MAS1 oncogene
Mas-related G protein-coupled receptor a
angiotensin-(1-7) receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012757.2NP_036889.1  proto-oncogene Mas

    See identical proteins and their annotated locations for NP_036889.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078884
    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Related
    ENSRNOP00000020100, ENSRNOT00000020100
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    48076768..48108218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008758729.1XP_008756951.1  

    See identical proteins and their annotated locations for XP_008756951.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  2. XM_008758728.1XP_008756950.1  

    See identical proteins and their annotated locations for XP_008756950.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  3. XM_006227860.2XP_006227922.1  

    See identical proteins and their annotated locations for XP_006227922.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  4. XM_006227859.2XP_006227921.1  

    See identical proteins and their annotated locations for XP_006227921.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  5. XM_008758726.1XP_008756948.1  

    See identical proteins and their annotated locations for XP_008756948.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  6. XM_006227867.2XP_006227929.1  

    See identical proteins and their annotated locations for XP_006227929.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  7. XM_008758727.1XP_008756949.1  

    See identical proteins and their annotated locations for XP_008756949.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  8. XM_008758730.1XP_008756952.1  

    See identical proteins and their annotated locations for XP_008756952.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)
  9. XM_006227868.2XP_006227930.1  

    See identical proteins and their annotated locations for XP_006227930.1

    UniProtKB/Swiss-Prot
    P12526
    UniProtKB/TrEMBL
    W8W3M4
    Conserved Domains (2) summary
    pfam00001
    Location:55279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21702
    Location:185241
    DUF1700; Protein of unknown function (DUF1700)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    43680754..43711122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)