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Tmbim6 transmembrane BAX inhibitor motif containing 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24822, updated on 8-May-2016
Official Symbol
Tmbim6provided by RGD
Official Full Name
transmembrane BAX inhibitor motif containing 6provided by RGD
Primary source
RGD:3842
See related
Ensembl:ENSRNOG00000055579
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Tegt; Cc1-27; Ab1-011; Ac1-149
Summary
Suppressor of apoptosis [RGD, Feb 2006]
Orthologs
Location:
7q36
Exon count:
14
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (141034980..141070269)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (115557801..115572802)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 40 homolog B Neighboring gene formin-like 3 Neighboring gene uncharacterized LOC103692980 Neighboring gene NCK-associated protein 5-like Neighboring gene uncharacterized LOC102546778

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
endoribonuclease inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
endoribonuclease inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
autophagy IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum calcium ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
lung development IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endoribonuclease activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of endoribonuclease activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of immunoglobulin secretion IEA
Inferred from Electronic Annotation
more info
 
negative regulation of immunoglobulin secretion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
negative regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
response to L-glutamate IEA
Inferred from Electronic Annotation
more info
 
response to L-glutamate ISO
Inferred from Sequence Orthology
more info
 
response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
response to unfolded protein IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
bax inhibitor 1
Names
BI-1
Bax inhibitor-1
testis enhanced gene transcript
testis-enhanced gene transcript protein
transmembrane BAX inhibitor motif-containing protein 6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019381.2NP_062254.2  bax inhibitor 1

    See identical proteins and their annotated locations for NP_062254.2

    Status: PROVISIONAL

    Source sequence(s)
    BC058478
    UniProtKB/Swiss-Prot
    P55062
    Related
    ENSRNOP00000073494, ENSRNOT00000084674
    Conserved Domains (1) summary
    cd10430
    Location:16228
    BI-1; BAX inhibitor (BI)-1

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    141034980..141070269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008765670.1XP_008763892.1  

    See identical proteins and their annotated locations for XP_008763892.1

    UniProtKB/TrEMBL
    Q7TMC1
    Related
    ENSRNOP00000069944, ENSRNOT00000091050
    Conserved Domains (1) summary
    cd10430
    Location:76290
    BI-1; BAX inhibitor (BI)-1
  2. XM_006257323.2XP_006257385.1  

    See identical proteins and their annotated locations for XP_006257385.1

    UniProtKB/Swiss-Prot
    P55062
    Related
    ENSRNOP00000074493, ENSRNOT00000088176
    Conserved Domains (1) summary
    cd10430
    Location:16228
    BI-1; BAX inhibitor (BI)-1

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    127009876..127024679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)