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SPESP1 sperm equatorial segment protein 1 [ Homo sapiens (human) ]

Gene ID: 246777, updated on 26-May-2016
Official Symbol
SPESP1provided by HGNC
Official Full Name
sperm equatorial segment protein 1provided by HGNC
Primary source
HGNC:HGNC:15570
See related
Ensembl:ENSG00000258484 HPRD:15436; MIM:609399; Vega:OTTHUMG00000133321
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ESP; SP-ESP
Summary
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]
Orthologs
Location:
15q23
Exon count:
2
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 15 NC_000015.10 (68930500..68946811)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (69222839..69239150)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene acidic nuclear phosphoprotein 32 family member A Neighboring gene ANP32A intronic transcript 1 Neighboring gene cytokine induced apoptosis inhibitor 1 pseudogene Neighboring gene NADPH oxidase, EF-hand calcium binding domain 5 Neighboring gene ATP binding cassette subfamily G member 2 (Junior blood group) pseudogene Neighboring gene uncharacterized LOC105370874

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC24663

Gene Ontology Provided by GOA

Process Evidence Code Pubs
acrosome reaction IBA
Inferred from Biological aspect of Ancestor
more info
 
fusion of sperm to egg plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
acrosomal vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
sperm equatorial segment protein 1
Names
equatorial segment protein
glycosylated 38 kDa sperm protein C-7/8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145658.3NP_663633.1  sperm equatorial segment protein 1 precursor

    See identical proteins and their annotated locations for NP_663633.1

    Status: REVIEWED

    Source sequence(s)
    AY358983, BC017998, BG720873, BM564110
    Consensus CDS
    CCDS10230.1
    UniProtKB/Swiss-Prot
    Q6UW49
    Related
    ENSP00000312284, OTTHUMP00000164446, ENST00000310673, OTTHUMT00000257125

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p2 Primary Assembly

    Range
    68930500..68946811
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 Alternate CHM1_1.1

    Range
    69340923..69357240
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)