Format

Send to:

Choose Destination

Pnmt phenylethanolamine-N-methyltransferase [ Rattus norvegicus (Norway rat) ]

Gene ID: 24661, updated on 8-May-2016
Official Symbol
Pnmtprovided by RGD
Official Full Name
phenylethanolamine-N-methyltransferaseprovided by RGD
Primary source
RGD:3361
See related
Ensembl:ENSRNOG00000046057
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
catalyzes the conversion of norepinephrine to epinephrine in catecholamine biosynthesis [RGD, Feb 2006]
Orthologs
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (86340893..86342501)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (86137019..86138436)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene StAR-related lipid transfer domain containing 3 Neighboring gene titin-cap Neighboring gene post-GPI attachment to proteins 3 Neighboring gene erb-b2 receptor tyrosine kinase 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
S-adenosylmethionine-dependent methyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
methyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
phenylethanolamine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
phenylethanolamine N-methyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
transferase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
S-adenosylhomocysteine metabolic process TAS
Traceable Author Statement
more info
PubMed 
S-adenosylmethionine metabolic process TAS
Traceable Author Statement
more info
PubMed 
adrenal gland development IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to dexamethasone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to peptide hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
epinephrine biosynthetic process IC
Inferred by Curator
more info
PubMed 
epinephrine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
epinephrine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
epinephrine biosynthetic process TAS
Traceable Author Statement
more info
PubMed 
methylation IEA
Inferred from Electronic Annotation
more info
 
norepinephrine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
response to activity IEP
Inferred from Expression Pattern
more info
PubMed 
response to cold IEP
Inferred from Expression Pattern
more info
PubMed 
response to corticosteroid IEP
Inferred from Expression Pattern
more info
PubMed 
response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
response to ether IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
response to immobilization stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to insulin IEP
Inferred from Expression Pattern
more info
PubMed 
response to isolation stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to peptide hormone IEP
Inferred from Expression Pattern
more info
PubMed 
response to water deprivation IEP
Inferred from Expression Pattern
more info
PubMed 
sensory perception of taste IEP
Inferred from Expression Pattern
more info
PubMed 
social behavior IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
perikaryon IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 
varicosity IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
phenylethanolamine N-methyltransferase
Names
PNMTase
noradrenaline N-methyltransferase
NP_113714.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031526.1NP_113714.1  phenylethanolamine N-methyltransferase

    See identical proteins and their annotated locations for NP_113714.1

    Status: PROVISIONAL

    Source sequence(s)
    X75333
    UniProtKB/Swiss-Prot
    P10937
    Related
    ENSRNOP00000067392, ENSRNOT00000073486
    Conserved Domains (1) summary
    pfam01234
    Location:13280
    NNMT_PNMT_TEMT; NNMT/PNMT/TEMT family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    86340893..86342501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    82132183..82134127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)