Format

Send to:

Choose Destination

Cant1 calcium activated nucleotidase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 246272, updated on 17-May-2016
Official Symbol
Cant1provided by RGD
Official Full Name
calcium activated nucleotidase 1provided by RGD
Primary source
RGD:628743
See related
Ensembl:ENSRNOG00000003239
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
srapy
Summary
hydrolyzes nucleoside 5'-diphosphates in the order UDP >GDP = IDP >>>CDP but not ADP, may be involved in glycosylation reactions related to quality control in the endoplasmic reticulum [RGD, Feb 2006]
Orthologs
Location:
10q32.3
Exon count:
5
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (107432500..107445634, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (107067498..107080632, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103693483 Neighboring gene lectin, galactoside-binding, soluble, 3 binding protein Neighboring gene uncharacterized LOC102548791 Neighboring gene C1q and tumor necrosis factor related protein 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
guanosine-diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
signal transducer activity ISO
Inferred from Sequence Orthology
more info
 
uridine-diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
Inferred from Electronic Annotation
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
proteoglycan biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
soluble calcium-activated nucleotidase 1
Names
SCAN-1
apyrase homolog
ectonucleoside triphosphate diphosphohydrolase 8
NP_653355.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144754.2NP_653355.1  soluble calcium-activated nucleotidase 1

    See identical proteins and their annotated locations for NP_653355.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097279
    UniProtKB/Swiss-Prot
    Q8K4Y7
    Related
    ENSRNOP00000059931, ENSRNOT00000066303
    Conserved Domains (1) summary
    pfam06079
    Location:115403
    Apyrase; Apyrase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    107432500..107445634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006247790.1XP_006247852.1  

    See identical proteins and their annotated locations for XP_006247852.1

    UniProtKB/Swiss-Prot
    Q8K4Y7
    Conserved Domains (1) summary
    pfam06079
    Location:115403
    Apyrase; Apyrase
  2. XM_006247789.2XP_006247851.1  

    See identical proteins and their annotated locations for XP_006247851.1

    UniProtKB/Swiss-Prot
    Q8K4Y7
    Conserved Domains (1) summary
    pfam06079
    Location:115403
    Apyrase; Apyrase

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    102197201..102210219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)