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Eda2r ectodysplasin A2 receptor [ Mus musculus (house mouse) ]

Gene ID: 245527, updated on 8-May-2016
Official Symbol
Eda2rprovided by MGI
Official Full Name
ectodysplasin A2 receptorprovided by MGI
Primary source
MGI:MGI:2442860
See related
Ensembl:ENSMUSG00000034457 Vega:OTTMUSG00000018046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Xedar; TNFRSF27; 9430060M22Rik
Orthologs
Location:
X; X C3
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (97333837..97377218, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (94529180..94572548, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 15-like Neighboring gene heat shock protein 90, alpha (cytosolic), class A member 1 pseudogene Neighboring gene Kruppel-like factor 17 pseudogene Neighboring gene mitochondrial ribosomal protein L10 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein M pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC124099

Gene Ontology Provided by MGI

Function Evidence Code Pubs
receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
intrinsic apoptotic signaling pathway by p53 class mediator IGI
Inferred from Genetic Interaction
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of JNK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of JNK cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
programmed cell death RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
tissue development IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular IGI
Inferred from Genetic Interaction
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
tumor necrosis factor receptor superfamily member 27
Names
EDA-A2 receptor
X linked ectodysplasin receptor
X-linked ectodysplasin-A2 receptor
ectodysplasin A2 isoform receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161432.1NP_001154904.1  tumor necrosis factor receptor superfamily member 27

    See identical proteins and their annotated locations for NP_001154904.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    AK029268, AK049134, AV580828, BC106845
    Consensus CDS
    CCDS30293.1
    UniProtKB/Swiss-Prot
    Q8BX35
    UniProtKB/TrEMBL
    Q3KP88
    Related
    ENSMUSP00000109463, OTTMUSP00000019575, ENSMUST00000113832, OTTMUST00000043558
    Conserved Domains (1) summary
    cd15838
    Location:3118
    TNFRSF27; Tumor necrosis factor receptor superfamily member 27 (TNFRSF27), also known as ectodysplasin A2 receptor (EDA2R) or X-linked ectodermal dysplasia receptor (XEDAR)
  2. NM_001161433.1NP_001154905.1  tumor necrosis factor receptor superfamily member 27

    See identical proteins and their annotated locations for NP_001154905.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' and 3' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AK049134, AL732487
    Consensus CDS
    CCDS30293.1
    UniProtKB/Swiss-Prot
    Q8BX35
    UniProtKB/TrEMBL
    Q3KP88
    Conserved Domains (1) summary
    cd15838
    Location:3118
    TNFRSF27; Tumor necrosis factor receptor superfamily member 27 (TNFRSF27), also known as ectodysplasin A2 receptor (EDA2R) or X-linked ectodermal dysplasia receptor (XEDAR)
  3. NM_175540.5NP_780749.3  tumor necrosis factor receptor superfamily member 27

    See identical proteins and their annotated locations for NP_780749.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AK029268, AK034909, AK049134, AV580828, BC106845
    Consensus CDS
    CCDS30293.1
    UniProtKB/Swiss-Prot
    Q8BX35
    UniProtKB/TrEMBL
    Q3KP88
    Related
    ENSMUSP00000041210, OTTMUSP00000019574, ENSMUST00000037353, OTTMUST00000043555
    Conserved Domains (1) summary
    cd15838
    Location:3118
    TNFRSF27; Tumor necrosis factor receptor superfamily member 27 (TNFRSF27), also known as ectodysplasin A2 receptor (EDA2R) or X-linked ectodermal dysplasia receptor (XEDAR)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    97333837..97377218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528026.2XP_006528089.1  

    See identical proteins and their annotated locations for XP_006528089.1

    UniProtKB/Swiss-Prot
    Q8BX35
    UniProtKB/TrEMBL
    Q3KP88
    Conserved Domains (1) summary
    cd15838
    Location:3118
    TNFRSF27; Tumor necrosis factor receptor superfamily member 27 (TNFRSF27), also known as ectodysplasin A2 receptor (EDA2R) or X-linked ectodermal dysplasia receptor (XEDAR)
  2. XM_006528025.2XP_006528088.1  

    See identical proteins and their annotated locations for XP_006528088.1

    UniProtKB/Swiss-Prot
    Q8BX35
    UniProtKB/TrEMBL
    Q3KP88
    Conserved Domains (1) summary
    cd15838
    Location:3118
    TNFRSF27; Tumor necrosis factor receptor superfamily member 27 (TNFRSF27), also known as ectodysplasin A2 receptor (EDA2R) or X-linked ectodermal dysplasia receptor (XEDAR)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    84324759..84367800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)