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Wasf2 WAS protein family, member 2 [ Mus musculus (house mouse) ]

Gene ID: 242687, updated on 28-May-2016
Official Symbol
Wasf2provided by MGI
Official Full Name
WAS protein family, member 2provided by MGI
Primary source
MGI:MGI:1098641
See related
Ensembl:ENSMUSG00000028868 Vega:OTTMUSG00000010477
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
WAVE2; AW742646; D4Ertd13e
Orthologs
Location:
4 D2.3; 4 66.22 cM
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (133130527..133199756)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (132686548..132754245)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 26615 Neighboring gene nuclear encoded tRNA glycine 1 (anticodon GCC) Neighboring gene microRNA 7017 Neighboring gene G-protein coupled receptor 3 Neighboring gene CD164 sialomucin-like 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
Rac protein signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin filament-based movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
ameboidal-type cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
lamellipodium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
megakaryocyte development IMP
Inferred from Mutant Phenotype
more info
PubMed 
movement of cell or subcellular component IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lamellipodium assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
SCAR complex ISO
Inferred from Sequence Orthology
more info
 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
early endosome IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular ISA
Inferred from Sequence Alignment
more info
PubMed 
lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium ISA
Inferred from Sequence Alignment
more info
PubMed 
ruffle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
wiskott-Aldrich syndrome protein family member 2
Names
WASP family protein member 2
protein WAVE-2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153423.6NP_700472.1  wiskott-Aldrich syndrome protein family member 2

    See identical proteins and their annotated locations for NP_700472.1

    Status: PROVISIONAL

    Source sequence(s)
    AL671858
    Consensus CDS
    CCDS18742.1
    UniProtKB/Swiss-Prot
    Q8BH43
    Related
    ENSMUSP00000081263, OTTMUSP00000011229, ENSMUST00000084241, OTTMUST00000024403
    Conserved Domains (1) summary
    pfam02205
    Location:433459
    WH2; WH2 motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    133130527..133199756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538849.2XP_006538912.1  

    See identical proteins and their annotated locations for XP_006538912.1

    UniProtKB/Swiss-Prot
    Q8BH43
    Conserved Domains (1) summary
    pfam02205
    Location:433459
    WH2; WH2 motif
  2. XM_006538850.2XP_006538913.1  

    See identical proteins and their annotated locations for XP_006538913.1

    UniProtKB/Swiss-Prot
    Q8BH43
    Conserved Domains (1) summary
    pfam02205
    Location:433459
    WH2; WH2 motif
  3. XM_006538848.2XP_006538911.1  

    See identical proteins and their annotated locations for XP_006538911.1

    UniProtKB/Swiss-Prot
    Q8BH43
    Conserved Domains (1) summary
    pfam02205
    Location:433459
    WH2; WH2 motif

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    131287726..131363266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)