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Add1 adducin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24170, updated on 26-May-2016
Official Symbol
Add1provided by RGD
Official Full Name
adducin 1provided by RGD
Primary source
RGD:2041
See related
Ensembl:ENSRNOG00000013039
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
may play a role in membrane cytoskeleton ion transport and signal transduction [RGD, Feb 2006]
Orthologs
Location:
14q21
Exon count:
18
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (81367466..81426610, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 14 NC_005113.3 (82054922..82114066, complement)

Chromosome 14 - NC_005113.4Genomic Context describing neighboring genes Neighboring gene NOP14 nucleolar protein Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene SH3-domain binding protein 2 Neighboring gene TNFAIP3 interacting protein 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC124621

Gene Ontology Provided by RGD

Function Evidence Code Pubs
T cell receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
actin binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding ISO
Inferred from Sequence Orthology
more info
 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
spectrin binding IEA
Inferred from Electronic Annotation
more info
 
spectrin binding ISO
Inferred from Sequence Orthology
more info
 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
structural molecule activity ISO
Inferred from Sequence Orthology
more info
 
transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
actin filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 
actin filament bundle assembly ISO
Inferred from Sequence Orthology
more info
 
barbed-end actin filament capping IEA
Inferred from Electronic Annotation
more info
 
barbed-end actin filament capping ISO
Inferred from Sequence Orthology
more info
 
cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cell volume homeostasis IEA
Inferred from Electronic Annotation
more info
 
cell volume homeostasis ISO
Inferred from Sequence Orthology
more info
 
cellular response to retinoic acid IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton organization TAS
Traceable Author Statement
more info
PubMed 
erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
hemoglobin metabolic process IEA
Inferred from Electronic Annotation
more info
 
hemoglobin metabolic process ISO
Inferred from Sequence Orthology
more info
 
homeostasis of number of cells within a tissue IEA
Inferred from Electronic Annotation
more info
 
homeostasis of number of cells within a tissue ISO
Inferred from Sequence Orthology
more info
 
in utero embryonic development IEA
Inferred from Electronic Annotation
more info
 
in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
ion transport NAS
Non-traceable Author Statement
more info
PubMed 
multicellular organism growth IEA
Inferred from Electronic Annotation
more info
 
multicellular organism growth ISO
Inferred from Sequence Orthology
more info
 
negative regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of angiogenesis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
F-actin capping protein complex IEA
Inferred from Electronic Annotation
more info
 
F-actin capping protein complex ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
focal adhesion IEA
Inferred from Electronic Annotation
more info
 
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
alpha-adducin
Names
adducin 1 (alpha)
alpha-ADD
erythrocyte adducin subunit alpha

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016990.2NP_058686.2  alpha-adducin

    See identical proteins and their annotated locations for NP_058686.2

    Status: PROVISIONAL

    Source sequence(s)
    BC107657
    UniProtKB/Swiss-Prot
    Q63028
    Related
    ENSRNOP00000018072, ENSRNOT00000018073
    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005113.4 Reference Rnor_6.0 Primary Assembly

    Range
    81367466..81426610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006251161.1XP_006251223.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  2. XM_006251159.1XP_006251221.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  3. XM_006251160.1XP_006251222.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  4. XM_008770249.1XP_008768471.1  

    UniProtKB/TrEMBL
    D3ZZ99
    Related
    ENSRNOP00000018340, ENSRNOT00000018340
    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  5. XM_006251165.2XP_006251227.1  

    See identical proteins and their annotated locations for XP_006251227.1

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  6. XM_008770250.1XP_008768472.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  7. XM_006251169.2XP_006251231.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  8. XM_006251168.2XP_006251230.1  

    See identical proteins and their annotated locations for XP_006251230.1

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  9. XM_006251167.2XP_006251229.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  10. XM_006251166.2XP_006251228.1  

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
  11. XM_006251164.2XP_006251226.1  

    See identical proteins and their annotated locations for XP_006251226.1

    Conserved Domains (1) summary
    cd00398
    Location:142352
    Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

Alternate Rn_Celera

Genomic

  1. AC_000082.1 Alternate Rn_Celera

    Range
    75033169..75091638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)